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[长期制动应激下大鼠血浆中的促肾上腺皮质激素、皮质酮和β-内啡肽]

[ACTH, corticosterone and beta-endorphin in the blood plasma of rats under prolonged immobilization stress].

作者信息

Kiiatkin E A, Polyntsev Iu V, Kushlinskiĭ N E, Amiragova M G

出版信息

Biull Eksp Biol Med. 1985 Aug;100(8):157-60.

PMID:2992628
Abstract

Radioimmunoassays were employed to study variation in the concentration of corticosterone, ACTH and beta-endorphin in rat blood plasma at different times of the 30-hour immobilization and under the effect of a short-term action of ecologically significant negative stimulation emanating from other animals. Both prolonged immobilization stress and short-term emotional reaction produced appreciable alterations in the blood plasma content of all the hormones under study. The findings indicate that variations in the corticosterone and beta-endorphin levels were in the best agreement.

摘要

采用放射免疫分析法研究了大鼠在30小时固定不同时间以及在来自其他动物的具有生态学意义的负面刺激短期作用下,血浆中皮质酮、促肾上腺皮质激素(ACTH)和β-内啡肽浓度的变化。长时间的固定应激和短期的情绪反应均使所研究的所有激素的血浆含量发生了明显改变。研究结果表明,皮质酮和β-内啡肽水平的变化最为一致。

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