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人类肛门直肠感觉功能研究。

Human studies of anorectal sensory function.

作者信息

Knowles Charles H

机构信息

Blizard Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

出版信息

Ir J Med Sci. 2018 Nov;187(4):1143-1147. doi: 10.1007/s11845-018-1847-5. Epub 2018 Jun 20.

DOI:10.1007/s11845-018-1847-5
PMID:29926337
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6209020/
Abstract

This review addresses three main questions: (1) Why is anorectal sensory function important in humans? (2) What is the evidence for anorectal sensory dysfunction in disease? (3) Can anorectal sensory function be modified for therapeutic benefit?

摘要

本综述探讨了三个主要问题

（1）为什么肛门直肠感觉功能在人类中很重要？（2）疾病中肛门直肠感觉功能障碍的证据是什么？（3）能否通过改善肛门直肠感觉功能来获得治疗益处？

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Human studies of anorectal sensory function.人类肛门直肠感觉功能研究。
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本文引用的文献

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Dietary and pharmacological treatment of abdominal pain in IBS.IBS 腹痛的饮食和药物治疗。
Gut. 2017 May;66(5):966-974. doi: 10.1136/gutjnl-2016-313425. Epub 2017 Feb 23.
2
Electrophysiological characterization of human rectal afferents.人类直肠传入神经的电生理特征
Am J Physiol Gastrointest Liver Physiol. 2016 Dec 1;311(6):G1047-G1055. doi: 10.1152/ajpgi.00153.2016. Epub 2016 Oct 27.
3
Randomized clinical trial of sacral nerve stimulation for refractory constipation.随机对照临床试验：骶神经刺激治疗难治性便秘
Br J Surg. 2017 Feb;104(3):205-213. doi: 10.1002/bjs.10326. Epub 2016 Oct 25.
4
A Joint Mechanism of Action for Sacral Neuromodulation for Bladder and Bowel Dysfunction?骶神经调节治疗膀胱和肠道功能障碍的联合作用机制？
Urology. 2016 Nov;97:13-19. doi: 10.1016/j.urology.2016.05.032. Epub 2016 May 24.
5
Pathophysiology of fecal incontinence differs between men and women: a case-matched study in 200 patients.大便失禁的病理生理学在男性和女性之间存在差异：一项针对200名患者的病例匹配研究。
Neurogastroenterol Motil. 2016 Oct;28(10):1580-8. doi: 10.1111/nmo.12858. Epub 2016 May 20.
6
Abnormal neuronal response to rectal and anal stimuli in patients with idiopathic fecal incontinence.特发性大便失禁患者对直肠和肛门刺激的异常神经元反应。
Neurogastroenterol Motil. 2015 Jul;27(7):954-62. doi: 10.1111/nmo.12567. Epub 2015 Apr 23.
7
Treatment efficacy of sacral nerve stimulation in slow transit constipation: a two-phase, double-blind randomized controlled crossover study.骶神经刺激治疗慢传输型便秘的疗效：一项两阶段、双盲随机对照交叉研究。
Am J Gastroenterol. 2015 May;110(5):733-40. doi: 10.1038/ajg.2015.101. Epub 2015 Apr 21.
8
Temporary sacral nerve stimulation in patients with fecal incontinence owing to rectal hyposensitivity: a prospective, double-blind study.直肠感觉减退所致大便失禁患者的临时骶神经刺激：一项前瞻性双盲研究
Surgery. 2015 Jan;157(1):56-63. doi: 10.1016/j.surg.2014.06.003.
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Unravelling Fowler's syndrome--current pathophysiological concepts.解析福勒综合征——当前的病理生理概念
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