UT Southwestern Medical Center.
UT Southwestern Medical Center, Children's Health-Children's Medical Center Dallas, Dallas, TX.
J Pediatr Gastroenterol Nutr. 2018 Oct;67(4):458-463. doi: 10.1097/MPG.0000000000002067.
There is little published experience with the use of over-the-scope clips (OTSCs) in pediatric patients. The aim of this study is to present our single-center experience utilizing OTSCs for nonvariceal gastrointestinal (GI) bleeding.
This is a retrospective case series of pediatric patients who underwent endoscopic management of GI bleeding during which OTSCs were used.
Eleven cases of OTSC utilization for hemostasis were identified in 10 unique patients between November 2014 and May 2016. The median age at intervention was 14.7 years (range 3.9-16.8 years) and median weight was 39 kg (range 17.4-85.8 kg). Technical success and hemostasis were achieved in all cases and there were no complications. Median follow-up was 32.9 months (range 21.2-39.4 months). All nonanastomotic ulcers (4), polypectomy bleeding (2), and sphincterotomy bleeding (1) had no evidence of recurrent GI bleeding at last follow-up. Two patients with anastomotic ulcerations required additional medical interventions.
Our series demonstrates the safety and effectiveness of the OTSCs in the pediatric population for acute GI bleeding throughout the GI tract. In our experience, it is effective for nonanastomotic ulcers, postpolypectomy bleeding, and postsphincterotomy bleeding even when other hemostatic techniques have failed. OTSCs may be less effective in the setting of anastomotic ulcerations, reaffirming the refractory nature of these lesions.
小儿患者使用内镜下全覆膜金属夹(OTSCs)的经验较少。本研究旨在介绍我们应用 OTSCs 治疗非静脉曲张性胃肠道(GI)出血的单中心经验。
这是一项回顾性病例系列研究,纳入了 2014 年 11 月至 2016 年 5 月期间因 GI 出血接受内镜治疗并使用 OTSCs 的患儿。
10 例患儿共 11 例使用 OTSCs 进行止血。干预时的中位年龄为 14.7 岁(范围 3.9-16.8 岁),中位体重为 39kg(范围 17.4-85.8kg)。所有病例均达到技术成功和止血,无并发症。中位随访时间为 32.9 个月(范围 21.2-39.4 个月)。所有非吻合口溃疡(4 例)、息肉切除出血(2 例)和括约肌切开出血(1 例)在最后一次随访时均无复发性 GI 出血证据。2 例吻合口溃疡患儿需要额外的药物治疗。
我们的系列研究表明,OTSCs 在小儿人群中治疗整个胃肠道急性 GI 出血是安全有效的。根据我们的经验,OTSCs 对非吻合口溃疡、息肉切除后出血和括约肌切开后出血有效,即使其他止血技术失败也是如此。OTSCs 在吻合口溃疡中的效果可能较差,这再次证实了这些病变的难治性。