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急性肾动脉栓塞:基于局部导管的动脉内溶栓治疗的作用

Acute renal artery embolisation: role of local catheter-based intra-arterial thrombolysis.

作者信息

Ganju Neeraj, Sondhi Sachin, Kandoria Arvind

机构信息

Cardiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India.

出版信息

BMJ Case Rep. 2018 Jun 21;2018:bcr-2018-224767. doi: 10.1136/bcr-2018-224767.

Abstract

A 45-year-old man without previous comorbidity presented to us with acute onset right-sided flank pain for last 14 hours. His general physical and systemic examination was unremarkable, and there were no clinical signs of peritonitis. The ultrasonography did not reveal any evidence of nephrolithiasis or hydronephrosis. His contrast-enhanced CT scan revealed hypoattenuated areas of right kidney and evidence of right renal artery thrombosis. He was immediately shifted to cardiac catheterisation lab, and his renal angiography showed thrombotic occlusion of right renal artery. The bolus dose of streptokinase (250 000 IU) was given locally in renal artery by right judkins catheter followed by systemic infusion of streptokinase (100 000 IU/hour) for 24 hours. After that he was started on low molecular weight heparin. Repeat renal angiography done after 5 days showed completely normal right renal artery. His cardiac and thrombophilia work up was negative, and he was discharged on antiplatelets, oral anticoagulants and statins.

摘要

一名45岁无既往合并症的男性因右侧胁腹急性疼痛14小时前来就诊。他的全身体格检查无异常,也没有腹膜炎的临床体征。超声检查未发现肾结石或肾积水的任何证据。他的增强CT扫描显示右肾有低密度区以及右肾动脉血栓形成的迹象。他立即被转至心脏导管室,肾血管造影显示右肾动脉血栓性闭塞。通过右Judkins导管在肾动脉局部给予大剂量链激酶(250 000 IU),随后全身输注链激酶(100 000 IU/小时),持续24小时。之后开始给予低分子量肝素。5天后复查肾血管造影显示右肾动脉完全正常。他的心脏和血栓形成倾向检查结果均为阴性,出院时服用抗血小板药物、口服抗凝剂和他汀类药物。

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