Anno Takayuki, Kobayashi Nobuyuki, Yamaguchi Takehiko
Department of Neurosurgery, Tochigi Medical Center Shimotsuga.
No Shinkei Geka. 2018 Jun;46(6):493-500. doi: 10.11477/mf.1436203758.
We report a rare case of an unruptured cerebral aneurysm in the left distal middle cerebral artery(MCA). A 76-year-old woman was referred to our department for unruptured cerebral aneurysms detected incidentally by magnetic resonance angiography. A left carotid angiogram revealed a saccular aneurysm arising in an arterial trunk unrelated to the branching zone of the distal MCA. The patient underwent an operation for trapping and excision of the saccular aneurysm in the distal MCA followed by end-to-end anastomosis. Histological analysis revealed an aneurysmally-dilated artery exhibiting thickened fibrous intima with foci of calcification and fragmented internal elastic lamina. Neither dissection nor infection were observed. The histological findings suggested that the aneurysm in this case was associated with arteriosclerotic change. Considering the medical history of the patient, we conclude that aging and hypertension are factors of the development of the cerebral aneurysm in our case, although the aneurysm is located in the distal MCA in which it is considered to low hemodynamic stress. We report this extremely rare case with a literature review.
我们报告了一例罕见的左侧大脑中动脉(MCA)远端未破裂脑动脉瘤病例。一名76岁女性因磁共振血管造影偶然发现未破裂脑动脉瘤而转诊至我科。左侧颈动脉血管造影显示一个囊状动脉瘤出现在与远端MCA分支区域无关的动脉干上。患者接受了手术,对远端MCA的囊状动脉瘤进行夹闭和切除,随后进行端端吻合。组织学分析显示动脉瘤样扩张的动脉,其纤维内膜增厚,有钙化灶和内弹力层断裂。未观察到夹层或感染。组织学结果表明,该病例中的动脉瘤与动脉硬化改变有关。考虑到患者的病史,我们得出结论,尽管该动脉瘤位于被认为血流动力学应力较低的远端MCA,但衰老和高血压是我们病例中脑动脉瘤发生发展的因素。我们通过文献回顾报告了这一极其罕见的病例。