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作者信息

Seidel Amélia Cristina, Campos Mariana Baldini, Campos Raquel Baldini, Harada Dérica Sayuri, Rossi Robson Marcelo, Cavalari Pedro, Miranda Fausto

机构信息

Universidade Estadual de Maringá - UEM, Departamento de Medicina, Maringá, PR, Brasil.

Universidade Estadual de Campinas - UNICAMP, Campinas, SP, Brasil.

出版信息

J Vasc Bras. 2017 Jan-Mar;16(1):4-10. doi: 10.1590/1677-5449.005216.

Abstract

BACKGROUND

Chronic venous disease demands clinical assessment, quantification of hemodynamic effects, and definition of anatomic distribution before diagnostic and treatment decisions can be made.

METHODS

This is a prospective study conducted in 2015 with a sample of 1,384 patients (2,669 limbs) aged from 17 to 85 years, 1,227 of whom were female. The most common symptoms reported in response to the questionnaire were pain, tiredness, feelings of heaviness, burning, cramps, and tingling. Subsets were formed on the basis of number of limbs distributed by sex, body mass index, and age. After definition of subsets, Doppler ultrasonography was used to conduct examinations of the great saphenous vein (GSV) and patients were distributed into three clinical groups (I: symptoms present and varicose veins absent, II: symptoms absent and varicose veins present and III: symptoms present and varicose veins present). Statistical analysis employed the chi-square test or Fisher’s exact test to test for homogeneity between groups. When associations significant to 5% were detected, odds ratios were calculated.

RESULTS

For both sexes, the chance of GSV insufficiency was 11.2 times greater in group III. Among cases with morbid obesity, the chance was 9.1 times greater in the same group. Additionally, patients in this group with ages ranging from 30 to 50 years exhibited a 43.1 times greater chance of GSV insufficiency.

CONCLUSIONS

Insufficiency of the GSV was significantly more frequent in group III, both overall and when considering only cases with morbid obesity, or cases in older age groups.

摘要

背景

在做出诊断和治疗决策之前,慢性静脉疾病需要进行临床评估、血流动力学效应量化以及解剖分布的界定。

方法

这是一项于2015年开展的前瞻性研究,样本包括1384例年龄在17至85岁之间的患者(2669条肢体),其中1227例为女性。问卷中报告的最常见症状为疼痛、疲劳、沉重感、烧灼感、痉挛和刺痛感。根据按性别、体重指数和年龄分布的肢体数量形成亚组。在定义亚组后,使用多普勒超声对大隐静脉(GSV)进行检查,并将患者分为三个临床组(I:有症状但无静脉曲张,II:无症状但有静脉曲张,III:有症状且有静脉曲张)。统计分析采用卡方检验或费舍尔精确检验来检验组间的同质性。当检测到显著性为5%的关联时,计算比值比。

结果

对于两性而言,III组大隐静脉功能不全的几率高11.2倍。在病态肥胖病例中,同一组的几率高9.1倍。此外,该组中年龄在30至50岁之间的患者大隐静脉功能不全的几率高43.1倍。

结论

总体而言,以及仅考虑病态肥胖病例或老年组病例时,III组大隐静脉功能不全的情况明显更常见。

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J Vasc Bras. 2017 Jan-Mar;16(1):4-10. doi: 10.1590/1677-5449.005216.

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本文引用的文献

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Incidence of chronic venous disease in the Edinburgh Vein Study.爱丁堡静脉研究中慢性静脉疾病的发病率。
J Vasc Surg Venous Lymphat Disord. 2013 Jan;1(1):59-67. doi: 10.1016/j.jvsv.2012.05.006. Epub 2012 Dec 8.
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The impact of obesity on venous insufficiency.肥胖对静脉功能不全的影响。
Phlebology. 2015 Aug;30(7):475-80. doi: 10.1177/0268355514551087. Epub 2014 Sep 5.
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Diagnosis of venous disease with duplex ultrasound.用双功超声诊断静脉疾病。
Phlebology. 2013 Mar;28 Suppl 1:158-61. doi: 10.1177/0268355513476653.
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Patterns of reflux in the great saphenous vein system.大隐静脉系统中的反流模式。
Phlebology. 2013 Mar;28 Suppl 1:39-46. doi: 10.1177/0268355513477021.

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