Office for Vein Diseases, Wunstorf, Germany.
Eur J Vasc Endovasc Surg. 2013 Jan;45(1):76-83. doi: 10.1016/j.ejvs.2012.10.014. Epub 2012 Dec 7.
Great saphenous vein (GSV) incompetence is involved in the majority of cases of varicose disease. Standardised pre-interventional assessment is required to analyse the relative merit of treatment modalities. We weighed GSV diameter measurement at the sapheno-femoral junction (SFJ) against measurement at the proximal thigh 15 cm distal to the groin (PT), established a conversion factor and applied it to selected literature data.
Legs with untreated isolated GSV reflux and varices limited to its territory and control legs were studied clinically, with duplex ultrasound and photoplethysmography. GSV diameters were measured at both the SFJ and the PT. A conversion factor was calculated and used to compare published data.
Of 182 legs, 60 had no GSV reflux (controls; group I), 51 had above-knee GSV reflux only (group II) and 71 had GSV reflux above and below knee (group III). GSV diameters in group I measured 7.5 mm (± 1.8) at the SFJ and 3.7 mm (± 0.9) at the PT. In groups II and III, they measured 10.9 mm (± 3.9) at the SFJ and 6.3 mm (± 1.9) at the PT (p < 0.001 each). Measurement at the PT revealed higher sensitivity and specificity to predict reflux and clinical class. Good correlation between sites of measurement (r = 0.77) allowed a conversion factor (SFJ = 1.767 * PT, PT = 0.566*SFJ) to be applied to pre-interventional data of published studies.
GSV diameter correlates with clinical class, measurement at the PT being more sensitive and more specific than measurement at the SFJ. Applying the conversion factor to published data suggests that some studies included patients with minor disease.
大隐静脉（GSV）功能不全是大多数静脉曲张疾病的原因。为了分析治疗方式的相对优势，需要进行标准化的术前评估。我们比较了在股隐交界（SFJ）处和腹股沟上方 15cm 处测量的 GSV 直径，建立了一个换算系数，并将其应用于部分文献数据。
对未经治疗的孤立性 GSV 反流和仅限于其区域的静脉曲张的腿部进行临床研究，采用双功能超声和光体积描记法。在 SFJ 和 PT 处测量 GSV 直径。计算换算系数并用于比较已发表的数据。
在 182 条腿中，60 条腿没有 GSV 反流（对照组；I 组），51 条腿只有膝上 GSV 反流（II 组），71 条腿有膝上和膝下 GSV 反流（III 组）。I 组在 SFJ 处的 GSV 直径为 7.5mm（±1.8），在 PT 处为 3.7mm（±0.9）。在 II 组和 III 组中，SFJ 处的直径为 10.9mm（±3.9），PT 处的直径为 6.3mm（±1.9）（均<0.001）。在 PT 处的测量显示出更高的预测反流和临床分级的灵敏度和特异性。测量部位之间具有良好的相关性（r=0.77），允许应用换算系数（SFJ=1.767PT，PT=0.566SFJ）来转换已发表研究的术前数据。
GSV 直径与临床分级相关，在 PT 处测量比在 SFJ 处测量更敏感和更特异。应用换算系数转换已发表的数据表明，一些研究纳入了病情较轻的患者。
