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混合性疟疾合并坏死性胰腺炎的成功治疗及文献综述

Successful management of necrotizing pancreatitis in mixed malaria and review of literature.

作者信息

Singh Jitendra, Dinkar Anju, Singh Rana Gopal, Kapoor Shishir

机构信息

Department of Medicine, Heritage Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

Department of Microbiology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.

出版信息

Trop Parasitol. 2018 Jan-Jun;8(1):8-11. doi: 10.4103/tp.TP_23_17. Epub 2018 May 28.

DOI:10.4103/tp.TP_23_17
PMID:29930900
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5991038/
Abstract

Malaria is one of the very common causes of fever in the Indian subcontinent with significant morbidity and mortality. In endemic areas, malaria infection may manifest with a variety of systemic complications ranging from mild to the life-threatening condition including atypical presentations and sometimes a clinical dilemma. We herein report a case of 35-year-old male laborer with complaints of fever, headache, and altered consciousness whose presentation was as case of clinical meningitis, developed acute hepatitis, kidney injury, and necrotizing pancreatitis. Later on, he diagnosed to have mixed malaria infection and improved well to antimalarial drugs with supportive management. In malaria, acute necrotizing pancreatitis is a rare and potentially fatal complication. We also accomplish a systematic review of literature for reports of acute pancreatitis due to infection. This report highlights the occurrence of several rare complications and systematic review of literature for acute pancreatitis due to malaria.

摘要

疟疾是印度次大陆发热的常见病因之一,具有较高的发病率和死亡率。在流行地区,疟疾感染可能表现出各种全身并发症,从轻症到危及生命的情况都有,包括非典型表现,有时还会造成临床诊断困境。我们在此报告一例35岁男性劳工,主诉发热、头痛和意识改变,其临床表现为临床性脑膜炎,随后发展为急性肝炎、肾损伤和坏死性胰腺炎。后来,他被诊断为混合性疟疾感染,经抗疟药物治疗及支持性治疗后恢复良好。在疟疾中,急性坏死性胰腺炎是一种罕见且可能致命的并发症。我们还对因感染导致急性胰腺炎的文献进行了系统综述。本报告强调了几种罕见并发症的发生情况以及对疟疾所致急性胰腺炎文献的系统综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8107/5991038/7ee9c5900be0/TP-8-8-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8107/5991038/72b4930619c6/TP-8-8-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8107/5991038/7ee9c5900be0/TP-8-8-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8107/5991038/72b4930619c6/TP-8-8-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8107/5991038/7ee9c5900be0/TP-8-8-g003.jpg

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本文引用的文献

1
Acute pancreatitis due to malaria: A case report of five patients and review of literature.疟疾所致急性胰腺炎:5例病例报告及文献复习
J Family Med Prim Care. 2016 Jul-Sep;5(3):691-694. doi: 10.4103/2249-4863.197302.
2
Malarial pancreatitis: Case report and systematic review of the literature.疟疾性胰腺炎:病例报告及文献系统综述
Indian J Crit Care Med. 2015 Dec;19(12):743-6. doi: 10.4103/0972-5229.171414.
3
Acute hemorrhagic necrotizing pancreatitis in falciparum malaria.恶性疟原虫所致急性出血坏死性胰腺炎
Rev Esp Enferm Dig. 2016 May;108(5):285-7. doi: 10.17235/reed.2015.3768/2015.
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Falciparum malaria complicated with acute pancreatitis: a report of case series.
J Vector Borne Dis. 2011 Sep;48(3):177-9.
5
Acute pancreatitis and subdural haematoma in a patient with severe falciparum malaria: case report and review of literature.一名重症恶性疟患者并发急性胰腺炎和硬膜下血肿:病例报告及文献复习
Malar J. 2008 May 30;7:97. doi: 10.1186/1475-2875-7-97.