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伴有散在脂肪组织的小脑后下动脉单纯性动脉畸形:病例报告

Pure arterial malformation of the posterior inferior cerebellar artery with interspersed adipose tissue: case report.

作者信息

Sorenson Thomas J, Brinjikji Waleed, Flemming Kelly D, Lanzino Giuseppe

机构信息

Departments of1Neurologic Surgery.

2Department of Radiology, University of Toronto, Ontario, Canada.

出版信息

J Neurosurg Pediatr. 2018 Sep;22(3):261-264. doi: 10.3171/2018.4.PEDS18135. Epub 2018 Jun 22.

Abstract

Incidental vascular lesions are being discovered at an increasing frequency due to widespread noninvasive brain imaging studies. One of these lesions has recently been termed a "pure arterial malformation" (PAM), which is defined as dilated, overlapping, and tortuous arteries forming a mass of arterial loops with a coil-like appearance in the absence of arteriovenous shunting. The pathogenesis of these lesions is not known, but a congenital etiology is suspected. The authors report the case of a 17-year-old female who was found to have a PAM of the posterior inferior cerebellar artery with adipose tissue interspersed within the arterial loops. The authors believe that this abnormal intracranial association between blood vessel and adipose tissue lends further support to the theory that PAMs are the result of a congenital malformation and are therefore safe to manage conservatively given their presumed benign natural history. Far from offering conclusive evidence, this unique case report adds to the growing body of PAM literature and strengthens an increasingly supported congenital theory of genesis.

摘要

由于广泛开展的无创性脑成像研究,偶然发现的血管病变的频率正在增加。其中一种病变最近被称为“纯动脉畸形”(PAM),其定义为在没有动静脉分流的情况下,扩张、重叠且迂曲的动脉形成一团呈线圈状外观的动脉环。这些病变的发病机制尚不清楚,但怀疑有先天性病因。作者报告了一例17岁女性,发现其小脑后下动脉存在PAM,动脉环内有脂肪组织散布。作者认为,这种血管与脂肪组织在颅内的异常关联进一步支持了PAM是先天性畸形结果的理论,因此鉴于其假定的良性自然病程,保守治疗是安全的。这一独特的病例报告远非提供确凿证据,而是增加了越来越多的PAM文献,并强化了越来越得到支持的先天性起源理论。

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