Xia Weidong, Zhong Xiangping, Ran Zhongying, Ding Dacheng, Zhang Meng, Tong Xiaoguang
Huanhu Hospital Affiliated to Tianjin Medical University, Tianjin, China.
The School of Medicine, Nankai University, Tianjin, China.
Neurosurg Rev. 2025 Jun 3;48(1):478. doi: 10.1007/s10143-025-03619-6.
Pure arterial malformations (PAMs) are rare cerebrovascular conditions characterized by dilated, tortuous arteries with a coil-like appearance, without venous components. Traditionally considered benign, PAMs are typically conservatively managed. However, their detection has increased with advancements in noninvasive imaging, and concerns about progression have emerged, with cases of cerebral hemorrhage or infarction being reported, raising questions about their benign nature and optimal treatment. Over nine years, our center surgically treated seven patients with symptomatic PAM, finding that PAMs are not invariably benign, especially in patients with aneurysm or prior stroke. We suggest that proactive surgical intervention, including malformation isolation or resection, complemented by cerebral bypass for vascular reconstruction, should be the preferred strategy. We also underscore the need for tailored management based on individual risk factors.
纯动脉畸形(PAM)是一种罕见的脑血管疾病,其特征是动脉扩张、迂曲,呈盘绕状外观,无静脉成分。传统上认为PAM是良性的,通常采用保守治疗。然而,随着无创成像技术的进步,其检出率有所增加,并且出现了对病情进展的担忧,有脑出血或梗死病例的报道,这引发了对其良性本质和最佳治疗方法的质疑。在九年多的时间里,我们中心对7例有症状的PAM患者进行了手术治疗,发现PAM并非总是良性的,尤其是在有动脉瘤或既往中风的患者中。我们建议,积极的手术干预,包括畸形隔离或切除,并辅以脑血管搭桥进行血管重建,应是首选策略。我们还强调了根据个体风险因素进行个性化管理的必要性。