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[来自毛鸡骨草叶的一种新的反式阿魏酸酰胺化合物]

[One new truxillic amide compound from Abrus mollis leaves].

作者信息

Yuan Xu-jiang, Zhang Ping, Li Chun-yang, Huo Wu-zhen, Lu Xiang-e, Wu Yan-hong

出版信息

Yao Xue Xue Bao. 2016 Oct;51(10):1595-9.

PMID:29932607
Abstract

The butanol extract part was extracted and isolated with water, alcohol and different organic solvents from Abrus mollis leaves. 6 compounds were isolated and purified using various column chromatographies and identified with the spectral techniques such as UV, MS, TLC, HPLC and NMR. The structures of 6 compounds were trigonelline (1), praline (2), alanine anhydride (3), (Z)-N-(4-hydroxycinnamoyl)tyrosine (4), (E)-N-(4-hydroxycinnamoyl)tyrosine (5), and abrusamide C (6). Compound 6 is a new compound, and compounds 1-4 were isolated from the plant for the first time.

摘要

采用水、乙醇及不同有机溶剂对毛鸡骨草叶的正丁醇提取物部位进行提取分离,通过多种柱色谱法分离纯化得到6个化合物,并采用紫外光谱(UV)、质谱(MS)、薄层色谱(TLC)、高效液相色谱(HPLC)及核磁共振(NMR)等光谱技术对其进行结构鉴定。6个化合物的结构分别为胡芦巴碱(1)、脯氨酸(2)、丙氨酸酐(3)、(Z)-N-(4-羟基肉桂酰基)酪氨酸(4)、(E)-N-(4-羟基肉桂酰基)酪氨酸(5)和鸡骨草酰胺C(6)。化合物6为新化合物,化合物1-4为首次从该植物中分离得到。

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