Shann F, Germer S
P N G Med J. 1979 Dec;22(4):72-5.
We have reviewed the clinical presentation of pneumonia to the Goroka paediatric ward. In comparison to survivors, children dying from pneumonia more often (p less than 0.05) had malnutrition (weight-for-age under 80%), anaemia (haemoglobin under 9g%), and a marked leucocytosis (total white cell count over 30,000 cells per c.m.m.). Children dying from pneumonia had been ill for longer and had been given more antibiotics prior to admission. There was no significant difference between children dying from pneumonia and survivors in age distribution, pulse rate, incidence of cardiac failure or duration of stay in hospital. 70% of the children dying from pneumonia at Goroka Hospital are infants under 12 months of age. Pneumococcal vaccine gives a poor antibody response in infants, and overseas studies using lung aspiration suggest that Haemophilus influenzae and Staphylococcus aureus might be causative organisms as well as Streptococcus pneumoniae. A study to determine the aetiology of pneumonia in Highlands children is required to enable a rational choice of routine antibiotic therapy and to plan further research on vaccination against pneumonia.
我们已对戈罗卡儿科病房收治的肺炎患儿临床表现进行了回顾。与存活患儿相比,死于肺炎的儿童更常出现(p小于0.05)营养不良(年龄别体重低于80%)、贫血(血红蛋白低于9克%)以及明显的白细胞增多(每立方毫米全白细胞计数超过30,000个细胞)。死于肺炎的儿童患病时间更长,入院前使用抗生素更多。死于肺炎的儿童与存活患儿在年龄分布、脉搏率、心力衰竭发生率或住院时间方面无显著差异。戈罗卡医院70%死于肺炎的儿童为12个月以下婴儿。肺炎球菌疫苗在婴儿中的抗体反应较差,国外采用肺穿刺的研究表明,流感嗜血杆菌和金黄色葡萄球菌可能与肺炎链球菌一样是致病微生物。需要开展一项研究以确定高地儿童肺炎的病因,从而能够合理选择常规抗生素治疗方案,并规划进一步的肺炎疫苗接种研究。