PLA Army General Hospital, Beijing, China.
Chaoyang Chinese Traditional and Western Medicine Emergency Medical Center, Beijing, China.
J Neurointerv Surg. 2019 Feb;11(2):205-210. doi: 10.1136/neurintsurg-2018-013886. Epub 2018 Jun 22.
Three-dimensional (3D) scans with flat detector angiographic systems are widely used for neurointerventions by providing detailed vascular information. However, its associated radiation dose and streak metal artifact generated by implanted treatment devices remain issues. This work evaluates the feasibility and clinical value of volume of interest imaging combined with metal artifact reduction (VOI+MAR) to generate high quality 3D images with reduced radiation dose and metal artifacts.
Full volume (FV) and VOI scans were acquired in 25 patients with intracranial aneurysms and treated with either endovascular coiling (n=9) or stent assisted coiling (n=16) procedures. FV and VOI scans were reconstructed with conventional DynaCT and VOI +MAR prototype software, respectively.
Quantitative evaluation results demonstrated that compared with standard FV DynaCT images, overall image quality was improved in the VOI+MAR reconstructed images, with streak metal artifacts considerably reduced or even removed; details of soft tissue in the vicinity of the metal devices was well preserved or recovered in the majority of cases. Radiation dose to patients calculated by dose area product was found to be significantly reduced using VOI scans.
This study confirmed the feasibility of using VOI+MAR prototype software to achieve high image quality of a small volume of clinical interest and to reduce radiation dose. This technique has potential to improve patient safety and treatment outcomes.
平板探测器血管造影系统的三维(3D)扫描通过提供详细的血管信息,广泛应用于神经介入。然而,其与植入治疗设备相关的辐射剂量和条纹状金属伪影仍然是问题。本研究评估了感兴趣区域成像(VOI)联合金属伪影减少(MAR)技术的可行性和临床价值,该技术可在降低辐射剂量和金属伪影的同时生成高质量的 3D 图像。
25 例颅内动脉瘤患者接受血管内弹簧圈栓塞术(n=9)或支架辅助弹簧圈栓塞术(n=16)治疗,分别采集全容积(FV)和感兴趣区域(VOI)扫描。使用常规 DynaCT 和 VOI+MAR 原型软件分别对 FV 和 VOI 扫描进行重建。
定量评估结果表明,与标准 FV DynaCT 图像相比,VOI+MAR 重建图像的整体图像质量得到改善,条纹状金属伪影明显减少甚至消除;大多数情况下,金属器械附近软组织的细节得到了很好的保留或恢复。通过剂量面积乘积计算得出,使用 VOI 扫描可显著降低患者的辐射剂量。
本研究证实了使用 VOI+MAR 原型软件实现小体积临床感兴趣区域的高质量成像并降低辐射剂量的可行性。该技术有可能提高患者的安全性和治疗效果。