Durrieu Geneviève, Dardonville Quentin, Clanet Michel, Montastruc Jean-Louis
Service de Pharmacologie Médicale et Clinique, Centre Midi-Pyrénées de PharmacoVigilance, de Pharmacoépidémiologie et d'Informations sur le Médicament, Pharmacopôle Midi-Pyrénées, INSERM, UMR 1027, CIC INSERM 1436, Toulouse, France.
Service de Neurologie, Centre Hospitalier Universitaire, Toulouse, France.
Fundam Clin Pharmacol. 2019 Feb;33(1):125-126. doi: 10.1111/fcp.12394. Epub 2018 Jul 12.
We describe one report of a cervical dysplasia in a patient receiving natalizumab for multiple sclerosis. Other cases were identified in the WHO's global individual case safety report database, VigiBase . These data underline the importance of monitoring HPV infection in patients with MS treated with natalizumab.
我们描述了1例接受那他珠单抗治疗多发性硬化症的患者发生宫颈发育异常的报告。在世界卫生组织的全球个体病例安全报告数据库VigiBase中还发现了其他病例。这些数据突显了对接受那他珠单抗治疗的多发性硬化症患者监测人乳头瘤病毒（HPV）感染的重要性。
