PACS-2 functions in colorectal cancer.
作者信息
Kveiborg Marie, Thomas Gary
机构信息
Biotech Research and Innovation Centre (BRIC), University of Copenhagen, Copenhagen, Denmark.
Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA.
出版信息
Aging (Albany NY). 2018 Jun 22;10(6):1190-1191. doi: 10.18632/aging.101489.
Abstract
摘要
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J Exp Med. 2018 Apr 2;215(4):1205-1225. doi: 10.1084/jem.20171696. Epub 2018 Feb 22.
2
Loss of PACS-2 delays regeneration in DSS-induced colitis but does not affect the model of colorectal cancer.PACS-2缺失会延迟葡聚糖硫酸钠（DSS）诱导的结肠炎的再生，但不影响结直肠癌模型。
Oncotarget. 2017 Nov 26;8(65):108303-108315. doi: 10.18632/oncotarget.22661. eCollection 2017 Dec 12.
3
Caught in the act - protein adaptation and the expanding roles of the PACS proteins in tissue homeostasis and disease.当场抓获——蛋白质适应以及PACS蛋白在组织稳态和疾病中的作用不断扩展
J Cell Sci. 2017 Jun 1;130(11):1865-1876. doi: 10.1242/jcs.199463. Epub 2017 May 5.
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EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients.肿瘤相关髓样细胞中的表皮生长因子受体促进小鼠结直肠癌的发展并与患者预后相关。
Gastroenterology. 2017 Jul;153(1):178-190.e10. doi: 10.1053/j.gastro.2017.03.053. Epub 2017 Apr 9.
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Nat Commun. 2015 Jun 25;6:7518. doi: 10.1038/ncomms8518.
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An ensemble prognostic model for colorectal cancer.结直肠癌的综合预后模型。
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Akt and 14-3-3 control a PACS-2 homeostatic switch that integrates membrane traffic with TRAIL-induced apoptosis.Akt和14-3-3调控一个PACS-2稳态开关，该开关将膜运输与TRAIL诱导的细胞凋亡整合在一起。
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