Indorewala Shabbir, Nemade Gaurav, Indorewala Abuzar, Mahajan Gauri
Indorewala ENT Hospital and Research Centre, Gaikwad Nagar, Behind Mahamarg Bus Stand, Nashik, Maharashtra, 422002, India.
Eur Arch Otorhinolaryngol. 2018 Aug;275(8):2177-2186. doi: 10.1007/s00405-018-5039-8. Epub 2018 Jun 23.
To see effectiveness of the senior author's repair technique for repair of large (equal to or larger than 10 mm) bony lateral skull base defects.
Retrospective.
Secondary/tertiary care center.
We performed retrospective review of 9 surgeries done in our institution between January 2010 and December 2013 for repair of large lateral bony skull base defects. We defined skull base defects extra-cranially and repaired them intra-cranially. We made an extracorporeal sandwich of autologous fascia-bone-fascia (fascia lata and nasal septal bone) and sewed it together to make it into a unit-sandwich graft. This extracorporeally sewed unit-sandwich graft was then inserted to close the large skull base defects either via (1) a cranial slit-window, or (2) the skull base defect itself. Since skull base is bony, bony repair is preferred. Bone plates that are easily available for skull base repair are calvarial and nasal septal bone. Occasionally, harvest of split calvarial bone carries risk of major complications. We preferred nasal septal bone. Harvesting of septal bone even in children using a posterior incision should not disturb the cartilage growth centers.
All nine patients were operated by this technique. We had four patients with cerebrospinal fluid leak, and five patients with brain herniation. All these patients had complete reversal of herniation of cranial contents and cessation of cerebrospinal fluid leak. On imaging, in 6 cases the bone graft remained in original intended position after 12 months of surgery. The bone graft was not identifiable in 3 cases.
The senior author's technique using autologous multi-layered graft is simple to master, repeatable and very effective.
观察资深作者用于修复大型(等于或大于10毫米)颅骨外侧基底骨缺损的修复技术的有效性。
回顾性研究。
二级/三级护理中心。
我们对2010年1月至2013年12月在本机构进行的9例修复大型外侧颅骨基底骨缺损的手术进行了回顾性分析。我们在颅外界定颅骨基底缺损,并在颅内进行修复。我们制作了自体筋膜-骨-筋膜(阔筋膜和鼻中隔骨)的体外三明治结构,并将其缝合在一起制成单元三明治移植物。然后将这个体外缝合的单元三明治移植物通过(1)颅骨裂隙窗或(2)颅骨基底缺损本身插入,以闭合大型颅骨基底缺损。由于颅骨基底是骨性的,因此首选骨性修复。易于用于颅骨基底修复的骨板是颅骨和鼻中隔骨。偶尔,获取劈开的颅骨会有发生重大并发症的风险。我们更倾向于使用鼻中隔骨。即使是儿童,采用后切口获取鼻中隔骨也不应干扰软骨生长中心。
所有9例患者均采用该技术进行手术。我们有4例脑脊液漏患者和5例脑疝患者。所有这些患者颅内内容物疝出均完全逆转,脑脊液漏停止。影像学检查显示,6例患者术后12个月骨移植物仍处于原预期位置。3例患者的骨移植物无法识别。
资深作者使用自体多层移植物的技术易于掌握、可重复且非常有效。