[关于胃癌转移所致骨髓弥漫性癌病的临床病理研究]
[Clinicopathological studies on disseminated carcinomatosis of the bone marrow occurring through metastasis of gastric carcinoma].
作者信息
Kamiya T, Honda K, Kizaki M, Maruyama T, Masuda T, Suzuki O, Ookawa H, Kiryu Y, Takahashi S, Yasumura K
出版信息
Gan No Rinsho. 1985 Jun;31(7):819-26.
Five cases of gastric carcinoma (one woman) were investigated. The average age of the patients was 44 and the clinical manifestation were lumbago, melena and fatigue. Two cases were Borrmann III, and other were Borrmann IV, IIc and IIc advanced, respectively. Three were signet-ring cell carcinoma and the other two were moderately differentiated and well-differentiated adenocarcinoma, respectively. All patients showed leukoerythroblastosis. Bone marrow specimens revealed myelofibrosis in three cases, while adenocarcinoma cells were also found in three. MHA or DIC was found in three patients, all of whom died of bleeding tendency. Mean survival time was 2.6 months. Thus, bone marrow carcinomatosis proved to be very severe.
对5例胃癌患者（1名女性）进行了调查。患者的平均年龄为44岁，临床表现为腰痛、黑便和疲劳。2例为Borrmann III型，其他分别为Borrmann IV型、IIc型和进展期IIc型。3例为印戒细胞癌，另外2例分别为中分化和高分化腺癌。所有患者均表现为幼稚粒-幼红细胞增多。骨髓标本显示3例有骨髓纤维化，同时在3例中也发现了腺癌细胞。3例患者出现微血管病性溶血性贫血（MHA）或弥散性血管内凝血（DIC），均死于出血倾向。平均生存时间为2.6个月。因此，骨髓转移癌被证明非常严重。
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