• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肾移植术后患者的肥胖风险因素

Obesity Risk Factors in Patients After Kidney Transplantation.

作者信息

Małgorzewicz S, Wołoszyk P, Chamienia A, Jankowska M, Dębska-Ślizień A

机构信息

Department of Clinical Nutrition, Medical University of Gdańsk, Gdańsk, Poland.

Department of General Nursing, Medical University of Gdańsk, Gdańsk, Poland.

出版信息

Transplant Proc. 2018 Jul-Aug;50(6):1786-1789. doi: 10.1016/j.transproceed.2018.02.099. Epub 2018 Mar 13.

DOI:10.1016/j.transproceed.2018.02.099
PMID:29937291
Abstract

BACKGROUND

Kidney transplantation is currently the best approach for renal replacement therapy. Compared with dialysis, it provides a better quality of life and improves patient prognosis. However, some evidence suggests that body composition could play a role in the complications observed in kidney transplant recipients (KTRs), and may influence survival. The purpose of this study was to assess the eating habits and body composition of KTRs.

METHODS

Seventy KTRs were included in this study. Anthropometry and body composition were performed using electronic-scale, dynamometer, and bioimpedance analyses. Dietary habits were investigated using the Food Frequency Questionnaire (FFQ6). Biochemical parameters were also determined.

RESULTS

Overweight and obesity were found in 33.8% and 21.1% of KTRs, respectively. High body mass index (BMI, >25) correlated positively with high body fat (r = 0.8, P < .05) and waist circumference (r = 0.7, P < .05). The mean percentage of body fat was 30.8 ± 9.3% (range, 13%-52%), fat tissue index was 12.4 ± 4.9, and lean tissue index (LTI) was 13.2 ± 2.2. Sarcopenia was recognized based on decreased LTI and decreased handgrip strength in 33.3% of KTRs with excess body weight. Patients with excess body mass consumed significantly (P < .05) more sugar and fruits.

CONCLUSION

A significant percentage of KTRs present with sarcopenic obesity. Excess body weight is associated with many factors, such as immunosuppressive therapy, low physical activity, and abnormal diet. Results based on the FFQ6 indicate a relationship between carbohydrate intake and excess body weight among those in the study group.

摘要

背景

肾移植是目前肾脏替代治疗的最佳方法。与透析相比,它能提供更好的生活质量并改善患者预后。然而,一些证据表明身体成分可能在肾移植受者(KTRs)出现的并发症中起作用,并可能影响生存率。本研究的目的是评估KTRs的饮食习惯和身体成分。

方法

本研究纳入了70名KTRs。使用电子秤、测力计和生物电阻抗分析进行人体测量和身体成分分析。使用食物频率问卷(FFQ6)调查饮食习惯。还测定了生化参数。

结果

分别有33.8%和21.1%的KTRs存在超重和肥胖。高体重指数(BMI,>25)与高体脂(r = 0.8,P <.05)和腰围(r = 0.7,P <.05)呈正相关。平均体脂百分比为30.8±9.3%(范围,13%-52%),脂肪组织指数为12.4±4.9,瘦组织指数(LTI)为13.2±2.2。在33.3%体重超标的KTRs中,根据LTI降低和握力下降诊断为肌肉减少症。体重超标的患者摄入的糖和水果明显更多(P <.05)。

结论

相当比例的KTRs存在肌肉减少性肥胖。体重超标与多种因素有关,如免疫抑制治疗、低体力活动和异常饮食。基于FFQ6的结果表明,研究组中碳水化合物摄入量与体重超标之间存在关联。

相似文献

1
Obesity Risk Factors in Patients After Kidney Transplantation.肾移植术后患者的肥胖风险因素
Transplant Proc. 2018 Jul-Aug;50(6):1786-1789. doi: 10.1016/j.transproceed.2018.02.099. Epub 2018 Mar 13.
2
Obesity After Successful Kidney Transplantation.肾移植成功后的肥胖问题
Transplant Proc. 2020 Oct;52(8):2352-2356. doi: 10.1016/j.transproceed.2020.02.091. Epub 2020 Apr 29.
3
The Associations of Muscle Strength, Muscle Mass, and Adiposity With Clinical Outcomes and Quality of Life in Prevalent Kidney Transplant Recipients.肌肉力量、肌肉质量和脂肪含量与流行肾移植受者临床结局和生活质量的关系。
J Ren Nutr. 2019 Nov;29(6):536-547. doi: 10.1053/j.jrn.2019.06.009. Epub 2019 Aug 12.
4
Weight gain in long-term survivors of kidney or liver transplantation--another paradigm of sarcopenic obesity?肾或肝移植长期存活者的体重增加——肌肉减少性肥胖的另一种模式?
Nutrition. 2012 Apr;28(4):378-83. doi: 10.1016/j.nut.2011.07.019. Epub 2012 Feb 2.
5
[Simple obesity in children. A study on the role of nutritional factors].[儿童单纯性肥胖。营养因素作用的研究]
Med Wieku Rozwoj. 2006 Jan-Mar;10(1):3-191.
6
High rates of central obesity and sarcopenia in CKD irrespective of renal replacement therapy - an observational cross-sectional study.无论是否接受肾脏替代治疗,慢性肾脏病患者中心型肥胖和肌肉减少症的发生率均较高——一项观察性横断面研究。
BMC Nephrol. 2018 Oct 11;19(1):259. doi: 10.1186/s12882-018-1055-6.
7
Inverse relationship between "a body shape index" (ABSI) and fat-free mass in women and men: Insights into mechanisms of sarcopenic obesity.女性和男性的“身体形态指数”(ABSI)与去脂体重呈反比关系:对瘦体重肥胖机制的深入了解。
Clin Nutr. 2015 Apr;34(2):323-7. doi: 10.1016/j.clnu.2014.03.015. Epub 2014 Apr 13.
8
Chronic kidney disease and high eGFR according to body composition phenotype in adults with normal BMI.正常体重指数成年人中根据身体成分表型划分的慢性肾脏病与高估算肾小球滤过率
Nutr Metab Cardiovasc Dis. 2016 Dec;26(12):1088-1095. doi: 10.1016/j.numecd.2016.09.003. Epub 2016 Sep 17.
9
SARCOPENIA, OBESITY AND SARCOPENIC OBESITY IN LIVER TRANSPLANTATION: A BODY COMPOSITION PROSPECTIVE STUDY.肝移植中的肌肉减少症、肥胖症和肌肉减少性肥胖症:一项身体成分前瞻性研究。
Arq Bras Cir Dig. 2019;32(2):e1434. doi: 10.1590/0102-672020190001e1434. Epub 2019 Apr 29.
10
Genetics of dietary habits and obesity - a twin study.饮食习惯与肥胖的遗传学——一项双胞胎研究。
Dan Med Bull. 2010 Sep;57(9):B4182.

引用本文的文献

1
Skeletal muscle atrophy in clinical and preclinical models of chronic kidney disease: A systematic review and meta-analysis.慢性肾脏病临床和临床前模型中的骨骼肌萎缩:系统评价和荟萃分析。
J Cachexia Sarcopenia Muscle. 2024 Feb;15(1):21-35. doi: 10.1002/jcsm.13400. Epub 2023 Dec 7.
2
Immunosuppressive Therapy and Nutritional Status of Patients after Kidney Transplantation: A Protocol for a Systematic Review.肾移植术后患者的免疫抑制治疗与营养状况:一项系统评价方案
J Clin Med. 2023 Nov 6;12(21):6955. doi: 10.3390/jcm12216955.
3
Diagnosis, prevalence, and outcomes of sarcopenia in kidney transplantation recipients: A systematic review and meta-analysis.
肌肉减少症在肾移植受者中的诊断、患病率和结局:系统评价和荟萃分析。
J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):17-29. doi: 10.1002/jcsm.13130. Epub 2022 Nov 20.
4
The effect of calcineurin inhibitors on anthropometric measurements in kidney transplant recipients.钙调磷酸酶抑制剂对肾移植受者人体测量学指标的影响。
BMC Nephrol. 2022 Nov 19;23(1):375. doi: 10.1186/s12882-022-03004-1.
5
Deterioration of presarcopenia and its risk factors following kidney transplantation.移植术后预肌少症的恶化及其危险因素。
Clin Exp Nephrol. 2020 Apr;24(4):379-383. doi: 10.1007/s10157-019-01835-1. Epub 2019 Dec 26.