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[脑干听觉诱发电位(BERA)电位幅度的刺激水平依赖性]

[Stimulus level dependence of BERA potential amplitudes].

作者信息

Hoth S

出版信息

Laryngol Rhinol Otol (Stuttg). 1985 Jul;64(7):368-74.

PMID:2993769
Abstract

The observed stimulus level dependence of early acoustic evoked potential amplitudes suggests that two different mechanism contribute to neural activity: A first mechanism yields neural activity immediately above the hearing threshold, the activity increasing up to a maximum value which is attained at a stimulus intensity of approximately 40 dB HL. At this level, the onset of a second mechanism is observed, which produces increasing neural activity and exhibits saturation behaviour at high stimulus intensities. A mathematical amplitude intensity characteristic is presented which can be calculated on the basis of simple and plausible assumptions. It is in excellent agreement with the experimental data. Furthermore, in the case of damaged hair cells but undamaged nerve fibres, the mathematical approach leads directly to the steep amplitude characteristic as it is often observed in the case of recruitment.

摘要

早期听觉诱发电位幅度对刺激强度的依赖性表明,有两种不同机制对神经活动有贡献:第一种机制在刚刚高于听阈时产生神经活动,该活动随刺激强度增加直至在约40 dB HL的刺激强度时达到最大值。在此水平上,可观察到第二种机制开始起作用,它会产生不断增加的神经活动,并在高刺激强度下表现出饱和行为。给出了一种数学幅度强度特性,它可基于简单且合理的假设来计算。它与实验数据高度吻合。此外,在毛细胞受损但神经纤维未受损的情况下,该数学方法直接得出在重振情况下经常观察到的陡峭幅度特性。

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