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采用软骨移植的退缩袋切除术作为胆脂瘤的预防性手术。

Retraction pocket excision with cartilage grafting as a preventive surgery for cholesteatoma.

作者信息

Comacchio Francesco, Mion Marta, Pedruzzi Barbara

机构信息

Institute of Otolaryngology, Department of Neurosciences, Padova University, Via Giustiniani 2, 35121 Padova, Italy.

Institute of Otolaryngology, Ospedali Riuniti Padova Sud, Via Albere 30, 35043 Monselice, Italy.

出版信息

J Otol. 2017 Sep;12(3):112-116. doi: 10.1016/j.joto.2017.04.003. Epub 2017 Apr 28.

Abstract

AIMS

The goal of the present study is to summarize our experience on surgical management of retraction pockets (RP) as a preventive tool against cholesteatomas.

METHODS

Twenty-five ears have been followed up for a mean period of 6.16 ± 4.35 years (from 1 to 17 years). The sample presented a mean age of 47.56 ± 19.11 years (from 16 to 73 years). All patients underwent cartilage graft surgery. Furthermore 10 (40%) underwent tympanoplasty (TPL) type I, 14 (56%) TPL type II and 1 (4%) TPL type V.

RESULTS

Eleven ears (44%) showed cholesteatoma: all these cases were stage III according to Charachon staging, and stage IV or V according to Gersdorff classification. Twelve patients (48%) showed erosion of the ossicular chain. Of these, five were associated with cholesteatoma and seven only with retraction. The recurrence rate of cholesteatoma was 12%. None of the patients with a stage II or III RP (according to Gersdorff classification) developed cholesteatoma. The recurrence of RP was 0%.In regards to literature review, seven references were selected. These studies showed a success rate ranging from 79.1% to 88%, while recurrences of RP varied from 6.4% to 13%. Only one study specified a recurrence rate of cholesteatoma of 28%.

CONCLUSIONS

Surgical treatment of stages II and III RP is an effective tool to prevent cholesteatoma formation. The presence of keratin accumulation and cholesteatoma at the RP (stages IV and V, according to Gersdorff) are the real predictors of poor prognosis.

摘要

目的

本研究的目的是总结我们在将退缩袋(RP)作为预防胆脂瘤的工具进行外科治疗方面的经验。

方法

对25只耳朵进行了平均6.16±4.35年(1至17年)的随访。样本的平均年龄为47.56±19.11岁(16至73岁)。所有患者均接受了软骨移植手术。此外,10例(40%)接受了I型鼓室成形术(TPL),14例(56%)接受了II型TPL,1例(4%)接受了V型TPL。

结果

11只耳朵(44%)出现胆脂瘤:根据查拉雄分期,所有这些病例均为III期,根据格尔斯多夫分类为IV期或V期。12例患者(48%)出现听骨链侵蚀。其中,5例与胆脂瘤相关,7例仅与退缩有关。胆脂瘤的复发率为12%。II期或III期RP(根据格尔斯多夫分类)的患者均未发生胆脂瘤。RP的复发率为0%。关于文献综述,选择了7篇参考文献。这些研究显示成功率在79.1%至88%之间,而RP的复发率在6.4%至13%之间。只有一项研究明确胆脂瘤的复发率为28%。

结论

II期和III期RP的外科治疗是预防胆脂瘤形成的有效工具。RP处(根据格尔斯多夫分类为IV期和V期)角蛋白积聚和胆脂瘤的存在是预后不良的真正预测因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1fe6/5963460/ab5dd0aa3a91/gr1.jpg

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