XIAP处于细胞死亡与炎症的交叉点。 - Suppr

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超能文献

XIAP at the crossroads of cell death and inflammation.

作者信息

Vucic Domagoj

机构信息

Genentech, South San Francisco, CA, USA.

出版信息

Oncotarget. 2018 Jun 8;9(44):27319-27320. doi: 10.18632/oncotarget.25363.

DOI:10.18632/oncotarget.25363

PMID:29937987

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6007953/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/13c1/6007953/a35ec0d31abe/oncotarget-09-27319-g001.jpg

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IAPs Regulate Distinct Innate Immune Pathways to Co-ordinate the Response to Bacterial Peptidoglycans.IAPs 通过调控不同的固有免疫途径来协调对细菌肽聚糖的反应。

Cell Rep. 2018 Feb 6;22(6):1496-1508. doi: 10.1016/j.celrep.2018.01.024.

Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling.多种泛素连接方式调节RIP激酶介导的炎症和细胞死亡信号传导。

Cell Death Differ. 2017 Jul;24(7):1160-1171. doi: 10.1038/cdd.2017.33. Epub 2017 May 5.

Inhibitors of apoptosis (IAPs) regulate intestinal immunity and inflammatory bowel disease (IBD) inflammation.凋亡抑制蛋白（IAPs）调节肠道免疫和炎症性肠病（IBD）炎症。

Trends Mol Med. 2014 Nov;20(11):652-65. doi: 10.1016/j.molmed.2014.09.006. Epub 2014 Oct 1.

XIAP restricts TNF- and RIP3-dependent cell death and inflammasome activation.X连锁凋亡抑制蛋白限制肿瘤坏死因子和受体相互作用蛋白3依赖性细胞死亡及炎性小体激活。

Cell Rep. 2014 Jun 26;7(6):1796-808. doi: 10.1016/j.celrep.2014.05.008. Epub 2014 May 29.

Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling.XIAP BIR2 结构域中的致病突变会损害 NOD2 依赖性免疫信号转导。

EMBO Mol Med. 2013 Aug;5(8):1278-95. doi: 10.1002/emmm.201303090. Epub 2013 Jul 1.

The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.泛素连接酶 XIAP 招募 LUBAC 参与 NOD2 信号转导，在炎症和先天免疫中发挥作用。

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