Karina Martínez-Méndez Dilia, Semprún-Hernández Neomar, Coromoto Hernández-Valles Rosaura
Invest Clin. 2015 Dec;56(4):411-20.
Coccidioidomycosis is a systemic fungal infection endemic in the Americas, caused by a dimorphic fungus. Inhalation of arthroconidia transported by wind colonize lung tissue causing mycosis. Diagnosis is made through epidemiological and mycological study, complemented by histopathological, molecular and immune response. In Venezuela it has been reported since 1948 when Dr. Humberto Campins described the first case in Barquisimeto, Lara state. The fungal diseases in Venezuela are not mandatory notification,so that t6here is a serious underreporting in the annual statistics of the country; however, the working groups in Mycology manage to keep the data of the cases. The information provided by bioclimatic and environmental variables in endemic areas can contribute to the pursuit of ecological niches of the fungus in order to strengthen eco-epidemiological surveillance of clinical cases and research subclinical cases, strengthening the preventive health system and appropriate medical management of mycosis.
球孢子菌病是一种在美洲流行的全身性真菌感染,由一种双相真菌引起。吸入随风传播的关节孢子会在肺组织中定殖,从而引发真菌病。诊断通过流行病学和真菌学研究进行,并辅以组织病理学、分子学和免疫反应方面的检查。在委内瑞拉,自1948年温贝托·坎平斯博士在拉腊州巴基西梅托描述首例病例以来,就有相关报道。委内瑞拉的真菌病并非强制通报疾病,因此该国年度统计数据中存在严重的漏报情况;然而,真菌学工作组设法保留了病例数据。流行地区生物气候和环境变量提供的信息有助于探寻真菌的生态位,以加强对临床病例的生态流行病学监测并研究亚临床病例,从而加强预防性卫生系统以及对真菌病进行适当的医疗管理。