Steiner I, Argov Z, Cahan C, Abramsky O
Neurology. 1985 Oct;35(10):1473-5. doi: 10.1212/wnl.35.10.1473.
Guillain-Barré syndrome (GBS) appeared in four patients 1 to 2 weeks after epidural anesthesia. In all patients, clinical diagnosis was confirmed by CSF findings and nerve conduction velocity studies. Although epidural anesthesia has not been listed as an antecedent event in GBS, evidence for the relationship has been previously reported. Interaction between the anesthetic agents and peripheral nervous system myelin or local trauma to roots may initiate a cascade of immunologic events that result in the demyelinating neuropathy.
4例患者在硬膜外麻醉后1至2周出现吉兰-巴雷综合征（GBS）。所有患者的临床诊断均经脑脊液检查结果和神经传导速度研究证实。尽管硬膜外麻醉未被列为GBS的前驱事件，但此前已有关于二者关系的证据报道。麻醉剂与周围神经系统髓鞘之间的相互作用或神经根的局部创伤可能引发一系列免疫事件，导致脱髓鞘性神经病。
