Nimmagadda Usharani, Salem M Ramez, Voronov Dimitry, Knezevic Nebojsa Nick
Middle East J Anaesthesiol. 2016 Oct;23(6):605-9.
Background: Preoxygenation before anesthetic induction is a widely accepted maneuver to increase oxygen reserves and delay desaturation during apnea. There is limited data regarding the use of the NuMask® in the perioperative setting, and no data as to its efficacy in achieving maximal preoxygenation. We hypothesize that the NuMask® may be a useful alternative to the face mask in achieving maximal preoxygenation. Methods: After IRB approval, the NuMask® was compared with the classic face mask with respect to achieving maximal pre-oxygenation in 30 healthy volunteers using tidal volume breathing. All volunteers were tested for three periods of 5 minutes intervals and the following parameters were recorded every 30 seconds: inspired, and end-tidal oxygen concentration and endtidal carbon dioxide concentration. Results: The mean ETO2 of ≥90% was achieved with both masks at 3.5 minutes (SD = 1.62 and 1.98 for facemask and NuMask® respectively) and thereafter the ETO2 remained above 90%. There were no statistical differences noted in FiO2 and ETO2 between the face mask and the NuMask® in the same time periods. ETCO2 values were also not statistically different between the two masks. Conclusions: The study showed that the NuMask® is as effective as the classic face mask in achieving maximal pre-oxygenation during tidal volume breathing. Introduction
麻醉诱导前的预充氧是一种广泛接受的操作，可增加氧储备并延迟呼吸暂停期间的去饱和。关于围手术期使用NuMask®的数据有限，且尚无关于其实现最大预充氧效果的数据。我们假设NuMask®在实现最大预充氧方面可能是面罩的一种有用替代方法。方法：经机构审查委员会（IRB）批准后，在30名健康志愿者中，比较了NuMask®和经典面罩在潮气量呼吸时实现最大预充氧的情况。所有志愿者均以5分钟为间隔进行三个阶段的测试，每30秒记录以下参数：吸入氧浓度、呼气末氧浓度和呼气末二氧化碳浓度。结果：两种面罩均在3.5分钟时达到平均呼气末氧浓度（ETO2）≥90%（面罩和NuMask®的标准差分别为1.62和1.98），此后ETO2保持在90%以上。在同一时间段内，面罩和NuMask®之间的吸入氧浓度（FiO2）和ETO2无统计学差异。两种面罩之间的呼气末二氧化碳（ETCO2）值也无统计学差异。结论：该研究表明，在潮气量呼吸期间实现最大预充氧方面，NuMask®与经典面罩一样有效。引言
