Holton Sara, Papanikolaou Vicki, Hammarberg Karin, Rowe Heather, Kirkman Maggie, Jordan Lynne, McNamee Kathy, Bayly Chris, McBain John, Sinnott Vikki, Fisher Jane
a Jean Hailes Research Unit , Monash University , Melbourne , VIC , Australia.
b Family Planning Victoria , Box Hill , VIC , Australia.
Eur J Contracept Reprod Health Care. 2018 Aug;23(4):282-287. doi: 10.1080/13625187.2018.1483020. Epub 2018 Jun 25.
Women with polycystic ovary syndrome (PCOS) are usually told that the condition is associated with fertility difficulties. However, little is known about their fertility management including contraceptive use, childbearing desires, and pregnancy outcomes.
To compare the fertility management experiences and outcomes of Australian women with and without PCOS.
The 2013 Australian electoral roll was used to identify a random sample of 18- to 50-year-old women who were sent the Understanding Fertility Management in Australia survey to be completed anonymously. Factors associated with fertility management and outcomes were identified in multivariable analyses.
Among the 1543 women who completed and returned the survey, 113 (7.3%) reported having PCOS. Women with PCOS reported a similar rate of current contraceptive use as women without PCOS (50.4% vs. 52.6%, p = .66). However, they were significantly younger at first pregnancy (24.9 vs. 26.8 years, p = .015), more likely to have consulted a health professional about fertility management (OR: 3.86, 95% CI: 2.50-5.96, p < .001), and perceive that it would be difficult to conceive (OR: 2.31, 95% CI: 1.41-3.79, p = .001) than women without PCOS. There were no significant differences in the number of desired children, unintended pregnancies, live births, abortions or miscarriages between women with and without PCOS.
These findings indicate that women with PCOS need more nuanced information about their fertility potential. While they may experience fertility difficulties because of their condition, they should also be informed that they can conceive spontaneously and need reliable contraception to avoid pregnancy when it is not wanted.
患有多囊卵巢综合征(PCOS)的女性通常被告知该疾病与生育困难有关。然而,对于她们的生育管理,包括避孕措施的使用、生育意愿和妊娠结局,人们了解甚少。
比较患有和未患有PCOS的澳大利亚女性的生育管理经历和结局。
利用2013年澳大利亚选民登记册随机抽取18至50岁的女性样本,向她们发送《澳大利亚生育管理认知》调查问卷,要求她们匿名填写。在多变量分析中确定与生育管理及结局相关的因素。
在1543名完成并返回调查问卷的女性中,113名(7.3%)报告患有PCOS。患有PCOS的女性当前避孕措施的使用率与未患PCOS的女性相似(50.4%对52.6%,p = 0.66)。然而,她们首次怀孕时的年龄显著更小(24.9岁对26.8岁,p = 0.015),更有可能就生育管理咨询过健康专家(比值比:3.86,95%置信区间:2.50 - 5.96,p < 0.001),并且比未患PCOS的女性更认为受孕困难(比值比:2.31,95%置信区间:1.41 - 3.79,p = 0.001)。患有和未患有PCOS的女性在期望子女数量、意外怀孕、活产、流产或自然流产方面没有显著差异。
这些发现表明,患有PCOS的女性需要关于其生育潜力的更细致入微的信息。虽然她们可能因其病情而经历生育困难,但也应告知她们能够自然受孕,并且在不想要孩子时需要可靠的避孕措施来避免怀孕。