Brain and Mind Centre, University of Sydney, 94 Mallet Street, Camperdown, Sydney, NSW, Australia.
Brain and Mind Centre, University of Sydney, 94 Mallet Street, Camperdown, Sydney, NSW, Australia; Sunshine Coast Mind and Neuroscience Thompson Institute, University of the Sunshine Coast, Birtinya, Queensland, Australia.
J Affect Disord. 2018 Oct 1;238:563-569. doi: 10.1016/j.jad.2018.06.032. Epub 2018 Jun 14.
Mental disorders and suicidal thoughts and behaviours are common in help-seeking youth. Few studies report the longitudinal associations between these phenomena and clinical and functional outcomes. This study examined whether prior suicide attempts predict poorer outcomes in mental health service attendees.
Clinical and functional data from 1143 individuals (aged 12-30) attending a primary care-based mental health service in Australia were collected over 3-60 months (median = 21 months). Odds ratios (OR) with 95% confidence intervals for the effect of a prior suicide attempt on follow-up outcomes were estimated (adjusted for confounders).
Prior suicide attempts were common (n = 164; 14%) and prospectively associated with suicidal thoughts (OR = 1.71), suicide attempts (OR = 2.59), self-harm (OR = 1.71), an increased likelihood of being diagnosed with bipolar disorder (OR = 2.99), and the onset of an alcohol/substance use disorder (OR = 2.87). Over the course of care, no suicide attempts were reported in 1052 (92%) individuals, but 25 (2%) had recurrent attempts, and 66 (6%) had new onset of an attempt. New onset was associated with being female and previous suicidal ideation or self-harm; recurrent attempts were associated with being older and comorbid alcohol/substance use disorder.
The cohort includes only individuals who remained in clinical contact, and the consistency of their documentation varied (across clinicians and over time).
Young people with prior suicide attempts are vulnerable to ongoing suicidal behaviours, and poorer clinical and functional outcomes. More intensive management strategies may be needed to directly address these behaviours and the long-term risks they confer. These behaviours also emerge over the course of care among those with no previous history, which has important implications for active service-level strategies that target these behaviours for all of those who present to such services.
精神障碍和自杀念头与行为在寻求帮助的年轻人中很常见。很少有研究报告这些现象与临床和功能结果之间的纵向关联。本研究旨在检验先前的自杀尝试是否预示着心理健康服务参与者的预后更差。
从澳大利亚一个基于初级保健的心理健康服务机构就诊的 1143 名 12-30 岁的个体收集了 3-60 个月(中位数=21 个月)的临床和功能数据。使用协方差分析(调整混杂因素后)估计了先前自杀尝试对随访结果的影响的比值比(OR)及其 95%置信区间。
先前的自杀尝试很常见(n=164;14%),并且与自杀念头(OR=1.71)、自杀尝试(OR=2.59)、自残(OR=1.71)、双相障碍的诊断几率增加(OR=2.99)和酒精/物质使用障碍的发病几率增加(OR=2.87)相关。在整个治疗过程中,1052 名(92%)患者未报告自杀尝试,但 25 名(2%)患者出现复发尝试,66 名(6%)出现新的自杀尝试。新发病例与女性以及先前的自杀意念或自残行为有关;复发尝试与年龄较大和合并酒精/物质使用障碍有关。
该队列仅包括仍处于临床接触的个体,并且他们的记录一致性(在不同临床医生和随时间推移)存在差异。
有过自杀尝试的年轻人易出现持续的自杀行为和较差的临床和功能结果。可能需要更密集的管理策略来直接处理这些行为及其带来的长期风险。在没有既往病史的患者中,这些行为也会在治疗过程中出现,这对针对这些行为的积极服务层面策略具有重要意义,这些策略适用于所有到此类服务机构就诊的患者。