Mărăşescu Petre Costin, Turcu Adina Andreea, Mercuţ Veronica, Scrieciu Monica, Mărgăritescu Claudiu, Ionovici Nina, Sălan Alex Ioan, Mărăşescu Felicia Ioana, Stan Mihaela Cristina
Department of Prosthetic Dentistry, Faculty of Dental Medicine, University of Medicine and Pharmacy of Craiova, Romania;
Rom J Morphol Embryol. 2018;59(1):147-152.
Tongue squamous carcinoma can be found in many forms, having a lot of risk factors, and whose morphological characteristics can be used as a prognostic. The purpose of this study was to histologically characterize a number of 54 patients diagnosed between 2012-2014, with tongue squamous carcinoma. Surgical resection specimens of tongue tumors were processed by paraffin inclusion technique. The diagnose samples were reevaluated according to the World Health Organization (WHO) criteria for head and neck tumors diagnosis, by screening the Hematoxylin-Eosin staining sections. The most common histopathological variety of tongue carcinoma observed in our cases was the non-keratinized form, the basaloid and sarcomatoid types of carcinoma being ranked on the last places. The study outlined the prevalence of non-keratinized forms of tongue squamous carcinoma and all types of tumoral invasion patterns have been observed in different percentages.
舌鳞状细胞癌有多种表现形式,存在诸多危险因素,其形态学特征可用于预后判断。本研究旨在对2012年至2014年间诊断为舌鳞状细胞癌的54例患者进行组织学特征分析。舌部肿瘤手术切除标本采用石蜡包埋技术处理。通过筛查苏木精-伊红染色切片,根据世界卫生组织(WHO)头颈部肿瘤诊断标准对诊断样本进行重新评估。在我们的病例中观察到的最常见的舌癌组织病理学类型是非角化型,基底样癌和肉瘤样癌排在最后。该研究概述了舌鳞状细胞癌非角化型的患病率,并且观察到了不同百分比的各种肿瘤浸润模式。