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[全球孕产妇死亡人数下降——但通常可预防]

[Maternal Deaths Worldwide Falling - But Commonly Preventable].

作者信息

Rath Werner, Tsikouras Panagiotis

机构信息

Medizinische Fakultät Gynäkologie und Geburtshilfe, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Kiel, Germany.

Department of Obstetrics and Gynecology, Alexandroupolis, Democritus University of Thrace, Greece.

出版信息

Z Geburtshilfe Neonatol. 2018 Aug;222(4):143-151. doi: 10.1055/a-0607-2816. Epub 2018 Jun 25.

Abstract

According to data from the WHO, maternal mortality ratio has dropped worldwide by 44% between 1990 and 2015, yet more than 300,000 mothers still die annually, about 99% of them in the developing countries. In some developed countries the incidence of maternal deaths has even increased during the past 2 decades. The leading causes of direct maternal deaths are haemorrhage (nearly 3-quarters from postpartum haemorrhage), pulmonary embolism including amniotic fluid embolism, and hypertensive disorders of pregnancy; the leading cause of indirect maternal deaths is cardiac disease of the mother. The most important step to prevent maternal deaths is the accurate evaluation of each death by a multidisciplinary committee of independent experts, followed by consensus-based agreement on the underlying cause of death, the quality of care, and whether or not the death was preventable. The UK Confidential Enquiries into Maternal Deaths and Morbidity are internationally recognized as the 'gold standard' in maternal mortality surveillance. Considering the 11 studies from different developed countries, nearly 50% of direct maternal deaths (range: 26-75%) are potentially preventable, most often those due to postpartum haemorrhage and hypertensive disorders of pregnancy, and the fewest of all due to amniotic fluid embolisms. The crucial point is to learn from failures leading to maternal deaths: each obstetric unit should scrutinise if and where the need for improvement exists to prevent severe maternal morbidity and mortality.

摘要

根据世界卫生组织的数据,1990年至2015年间,全球孕产妇死亡率下降了44%,但每年仍有超过30万孕产妇死亡,其中约99%发生在发展中国家。在一些发达国家,孕产妇死亡的发生率在过去20年中甚至有所上升。孕产妇直接死亡的主要原因是出血(近四分之三来自产后出血)、肺栓塞(包括羊水栓塞)和妊娠高血压疾病;孕产妇间接死亡的主要原因是母亲的心脏病。预防孕产妇死亡的最重要步骤是由独立专家组成的多学科委员会对每例死亡进行准确评估,随后就死亡的根本原因、护理质量以及死亡是否可预防达成基于共识的一致意见。英国孕产妇死亡和发病情况保密调查在孕产妇死亡率监测方面被国际公认为“金标准”。综合来自不同发达国家的11项研究,近50%的孕产妇直接死亡(范围:26%-75%)有可能预防,最常见的是产后出血和妊娠高血压疾病导致的死亡,而羊水栓塞导致的死亡最少。关键是要从导致孕产妇死亡的失败案例中吸取教训:每个产科单位都应审视是否以及在何处存在改进的必要性,以预防严重的孕产妇发病和死亡。

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