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一种对成年女性具有抗衰功效的痤疮治疗方案的疗效与耐受性:一项试点研究。

Efficacy and Tolerability of an Acne Treatment Regimen with Antiaging Benefits in Adult Women: A Pilot Study.

作者信息

Jiang Lily I, Hino Peter D, Parker Lydia, Stephens Thomas J, Mccook John, Gotz Vincent

机构信息

Drs. Jiang, Hino, and Stephens are with Thomas J. Stephens and Associates, Inc. in Richardson, Texas.

Dr. Parker is with the Parker Skin and Aesthetic Clinic in Beachwood, Ohio.

出版信息

J Clin Aesthet Dermatol. 2018 Jun;11(6):46-51. Epub 2018 Jun 1.

Abstract

The objective of this study was to assess clinical safety and efficacy of a novel acne treatment regimen in adult women. Participants in the study included an ethnically diverse group of adult women (n=24) with mild-to-moderate acne who were treated twice daily with a topical regimen (cleanser, acne cream, and rebalancing gel) for eight weeks. Following baseline assessments, subjects returned to clinic at Weeks 2, 4, and 8 for clinical assessments and self-assessment questionnaires. Twenty-one of the 24 enrolled women completed the eight-week clinical trial. Statistically significant clinical improvements were seen in both acne and aging parameters over time. The product regimen was well tolerated without adverse reactions commonly seen with topical acne products. The regimen demonstrated efficacy and tolerability in adult women with acne and signs of skin aging.

摘要

本研究的目的是评估一种新型痤疮治疗方案在成年女性中的临床安全性和有效性。该研究的参与者包括一组种族多样的成年女性(n=24),她们患有轻度至中度痤疮,每天接受两次局部治疗方案(洁面乳、痤疮霜和平衡凝胶),为期八周。在进行基线评估后,受试者在第2周、第4周和第8周返回诊所进行临床评估和自我评估问卷调查。24名入组女性中有21名完成了为期八周的临床试验。随着时间的推移,痤疮和衰老参数均出现了具有统计学意义的临床改善。该产品方案耐受性良好,没有出现局部痤疮产品常见的不良反应。该方案在患有痤疮和皮肤衰老迹象的成年女性中显示出有效性和耐受性。

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