Leutenegger A
Int Z Vitam Ernahrungsforsch Beih. 1979;18:113-7.
Trauma and stress can cause characteristic changes in metabolism: raised lipolysis and reduced glucose tolerance as well as major renal nitrogen losses are manifestations of a postoperative or posttraumatic excess of catabolism over anabolism. Excess catabolism is caused by immobilisation and inadequate oral or parenteral nutrition. Wasting in seriously ill patients for intensive treatment. Priority must be given to the prevention of insufficiencies of organs and systems, and to the elimination of stress factors. It is only then that mobilisation and the administration of calories and nitrogen will restore a normal anabolism-catabolism balance.
脂肪分解增加、葡萄糖耐量降低以及肾脏大量氮丢失，这些都是术后或创伤后分解代谢超过合成代谢的表现。分解代谢过度是由制动以及口服或肠外营养不足所致。重症患者在接受强化治疗时会出现消瘦。必须优先预防器官和系统功能不全，并消除应激因素。只有这样，进行活动以及给予热量和氮才能恢复正常的合成代谢与分解代谢平衡。
