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睾丸肿瘤患者妊娠特异性β1-糖蛋白(SP-1)的酶免疫测定

[Enzyme immunoassay for pregnancy-specific beta 1-glycoprotein (SP-1) in patients with testicular tumors].

作者信息

Schulze H, Schmechta H, Hallmann B, Ruttloff J, Porstmann T, Porstmann B

出版信息

Z Urol Nephrol. 1985 Jun;78(6):293-8.

PMID:2994322
Abstract

The use of a two-side-binding-enzyme-immunoassay for pregnancy-specific beta 1-glycoprotein (SP-1) in tumours of the testicles is described. The lower limit of evidence is with 4 ng/ml near to the physiological region. In 17 of 41 non-seminomatous germinal tumours of the testicles (41%) initially increased SP-1-serum concentrations were present, the other measuring values correlated with the course of the disease. In all tumours of the testicles with initially increased SP-1-titres the use of the SP-1-test gives a further possibility of the regulation of therapy and control of the course.

摘要

描述了一种用于检测睾丸肿瘤中妊娠特异性β1-糖蛋白(SP-1)的双侧结合酶免疫测定法。证据下限为4 ng/ml,接近生理范围。在41例睾丸非精原性生殖细胞肿瘤中有17例(41%)最初存在SP-1血清浓度升高,其他测量值与疾病进程相关。在所有最初SP-1滴度升高的睾丸肿瘤中,使用SP-1检测为治疗调整和病程控制提供了进一步的可能性。

相似文献

1
[Enzyme immunoassay for pregnancy-specific beta 1-glycoprotein (SP-1) in patients with testicular tumors].睾丸肿瘤患者妊娠特异性β1-糖蛋白(SP-1)的酶免疫测定
Z Urol Nephrol. 1985 Jun;78(6):293-8.
2
Non-seminomatous germ cell tumors of the testis. Immunohistochemical localization and serum levels of human chorionic gonadotropin (HCG) and pregnancy-specific beta-1 glycoprotein (SP-1); value of SP-1 as a tumor marker.睾丸非精原细胞瘤。人绒毛膜促性腺激素(HCG)和妊娠特异性β1糖蛋白(SP-1)的免疫组化定位及血清水平;SP-1作为肿瘤标志物的价值。
Oncodev Biol Med. 1982;3(5-6):409-22.
3
[Testicular tumors. Analysis of observations from the urological departments of Slovakia during 1965-1974].
Urol Nefrol (Mosk). 1978 Jan-Feb(1):48-53.
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Testicular tumours in infancy and childhood--a review of 10 germ cell tumours and 10 non germ cell tumours.婴幼儿及儿童期睾丸肿瘤——10例生殖细胞肿瘤与10例非生殖细胞肿瘤的综述
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