Schulze H, Schmechta H, Hallmann B, Ruttloff J, Porstmann T, Porstmann B
Z Urol Nephrol. 1985 Jun;78(6):293-8.
The use of a two-side-binding-enzyme-immunoassay for pregnancy-specific beta 1-glycoprotein (SP-1) in tumours of the testicles is described. The lower limit of evidence is with 4 ng/ml near to the physiological region. In 17 of 41 non-seminomatous germinal tumours of the testicles (41%) initially increased SP-1-serum concentrations were present, the other measuring values correlated with the course of the disease. In all tumours of the testicles with initially increased SP-1-titres the use of the SP-1-test gives a further possibility of the regulation of therapy and control of the course.
描述了一种用于检测睾丸肿瘤中妊娠特异性β1-糖蛋白(SP-1)的双侧结合酶免疫测定法。证据下限为4 ng/ml,接近生理范围。在41例睾丸非精原性生殖细胞肿瘤中有17例(41%)最初存在SP-1血清浓度升高,其他测量值与疾病进程相关。在所有最初SP-1滴度升高的睾丸肿瘤中,使用SP-1检测为治疗调整和病程控制提供了进一步的可能性。