Fukami T, Tsujioka H, Matsuoka S, Sorano S, Tohyama A, Yamamoto H, Nakamura S, Goto M, Matsuoka R, Eguchi F
Clin Exp Obstet Gynecol. 2016;43(6):800-802.
The present authors analyzed patients' backgrounds and pre-surgical findings to clarify the risk factors of rupture of fallopian tubal pregnancy. The surgical findings 113 cases were clearly diagnosed as fallopian tubal pregnancy with or without rupture. Twenty-six cases of fallopian tubal pregnancy were ruptured and 87 cases were not ruptured at the time of operation. The risk factors of fallopian tubal rupture were assessed by Chi-square for independence test and multiple regression analysis. Obesity (BMI over 26), prior birth history, social welfare entitlement, ultrasonography findings of fetal heart movement, and pre-surgical serum beta-hCG level more than 3,000 mIU/ml patient were significantly higher risk in fallopian tubal rupture. Fertility treatment patient were at significantly lower risk for fallopian tubal rupture. Higher beta-hCG levels, especially >3,000 mIU/ml is associated with increased risk of fallopian tubal rupture in ectopic pregnancy.
本文作者分析了患者的背景和术前检查结果，以阐明输卵管妊娠破裂的危险因素。113例手术结果被明确诊断为输卵管妊娠伴或不伴破裂。26例输卵管妊娠发生破裂，87例在手术时未破裂。通过卡方独立性检验和多元回归分析评估输卵管破裂的危险因素。肥胖（BMI超过26）、既往生育史、社会福利资格、超声检查发现胎心搏动以及术前血清β-hCG水平超过3000 mIU/ml的患者，输卵管破裂的风险显著更高。接受生育治疗的患者输卵管破裂风险显著更低。较高的β-hCG水平，尤其是>3000 mIU/ml，与异位妊娠中输卵管破裂风险增加相关。
