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第一秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC作为尼日利亚中北部锯木厂工人鼻炎的预测指标

FEV1, FVC, FEV1 /FVVC as predictors of rhinitis among saw mill workers in north central Nigeria.

作者信息

Dunga Jacob Amos, Alkali Nura Hamidu, Adamu Yakubu Mamman, Bathna Sule, Suleiman Yerima, Ukoli Christian, Musa Jafiada Jacob

出版信息

Niger J Med. 2016 Apr-Jun;25(2):152-8.

PMID:29944313
Abstract

BACKGROUND

Rhinitis is one of the commonest occupational related respiratory disorders that is only restricted to the upper airway but can involve the lower respiratory tract with considerable airflow limitation, this study was conducted assess the ventilator function of persons exposed to saw dust with rhinitis symptoms.

METHODS

This is a cross sectional study carried out among 200 randomly selected saw mill workers and 200 healthy staff of Jos University Teaching Hospital staff in Jos metropolis from September to November 2008. Data on sociodemographic variables, symptoms of rhinitis, etc was obtained using a modified semi structured British medical research council questionnaire while respiratory function data was measured using a spirometry.

RESULT

A total of 400 responds comprising of 200 saw mill workers and 200 controls participated in this study. Based on diagnostic criteria. 43% of the subjects fit into diagnosis of rhinitis, 33% had asthma symptoms and 24 % did not fit into any category compared to none of < 5% of the control group. The ventilatory function based on FEV1, FVC, FEV1/FVC ratio and PEFR showed a significant decline when matched with controls and predicted value, suggesting an airflow limitation among the rhinitis group.

CONCLUSION

Rhinitis associated with wood dust exposure is not restricted to airway but involves the entire respiratory tract with airflow limitation as one of its consequences.

摘要

背景

鼻炎是最常见的职业相关呼吸道疾病之一,通常仅局限于上呼吸道,但也可能累及下呼吸道,导致相当程度的气流受限。本研究旨在评估有鼻炎症状的木屑暴露者的通气功能。

方法

这是一项横断面研究,于2008年9月至11月在乔斯市随机选取200名锯木厂工人和200名乔斯大学教学医院的健康员工中进行。使用改良的半结构化英国医学研究委员会问卷获取社会人口统计学变量、鼻炎症状等数据,同时使用肺活量计测量呼吸功能数据。

结果

共有400名参与者,包括200名锯木厂工人和200名对照组。根据诊断标准,43%的受试者符合鼻炎诊断,33%有哮喘症状,24%不属于任何类别,而对照组中这一比例均小于5%。基于第一秒用力呼气容积(FEV1)、用力肺活量(FVC)、FEV1/FVC比值和呼气峰值流速(PEFR)的通气功能与对照组和预测值相比有显著下降,提示鼻炎组存在气流受限。

结论

与木屑暴露相关的鼻炎不仅局限于气道,还累及整个呼吸道,气流受限是其后果之一。

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