Hospital do Coração, São Paulo-SP, Brazil; Department of Physiotherapy, Communication Science & Disorders, Occupational Therapy, Medical School of the University of São Paulo, São Paulo, Brazil; Cardio-Pulmonary Department-Respiratory ICU, Pulmonary Division, Heart Institute, Hospital das Clínicas da FMUSP, University of Sao Paulo, São Paulo, Brazil.
University Hospital, Universidade de São Paulo, São Paulo, Brazil.
J Thorac Cardiovasc Surg. 2018 Dec;156(6):2170-2177.e1. doi: 10.1016/j.jtcvs.2018.05.004. Epub 2018 May 28.
Pulmonary impairment is a common complication after coronary artery bypass graft procedure and may be prevented or treated by noninvasive ventilation. Recruitment maneuvers include sustained airway pressure with high levels of positive end-expiratory pressure in patients with hypoxemia, favoring homogeneous pulmonary ventilation and oxygenation. This study aimed to evaluate whether noninvasive ventilation with recruitment maneuver could safely improve oxygenation in patients with atelectasis and hypoxemia who underwent a coronary artery bypass grafting procedure.
Thirty-four patients admitted to our intensive care unit undergoing mechanical ventilation after surgery, with ratio of arterial oxygen partial pressure to fraction of inspired oxygen < 300 and radiologic atelectasis score ≥2, were included. The control group consisted of 16 randomized patients and the recruitment group consisted of 18 patients. After extubation, noninvasive ventilation was applied for 30 minutes 3 times a day with positive end-expiratory pressure of 8 cm HO. The recruitment group received recruitment maneuver with positive end-expiratory pressure of 15 cm HO and 20 cm HO for 2 minutes each during noninvasive ventilation. We analyzed the arterial oxygen partial pressure in room air, radiologic atelectasis score, hemodynamic stability, and adverse events from extubation until discharge.
Arterial oxygen partial pressure increased 12.6% ± 6.8% in the control group and 23.3% ± 8.5% in the recruitment group (P < .001). The radiologic atelectasis score was completely improved for 94.4% of the recruitment group with no adverse events, whereas 87.5% of the control group presented some atelectasis (P < .001).
Noninvasive ventilation with recruitment maneuvers is safe, improves oxygenation, and reduces atelectasis in patients undergoing coronary artery bypass.
肺部损伤是冠状动脉旁路移植手术后的常见并发症,可以通过无创通气来预防或治疗。肺复张手法包括对低氧血症患者施以持续气道正压和高水平呼气末正压,以促进肺通气和氧合的均匀分布。本研究旨在评估对接受冠状动脉旁路移植手术且存在肺不张和低氧血症的患者施以带肺复张手法的无创通气是否能安全改善氧合。
共纳入 34 名术后转入我们重症监护病房并接受机械通气、动脉血氧分压与吸入氧分数比值<300 且影像学肺不张评分≥2 的患者。对照组为 16 名随机患者,复张组为 18 名患者。拔管后,两组患者均每天接受 3 次、每次 30 分钟的无创通气,呼气末正压为 8cmH₂O。复张组在无创通气期间接受每次 2 分钟、呼气末正压为 15cmH₂O 和 20cmH₂O 的肺复张手法。我们分析了两组患者在拔除气管导管直至出院期间的动脉血氧分压、影像学肺不张评分、血流动力学稳定性和不良事件。
对照组患者的动脉血氧分压增加了 12.6%±6.8%,而复张组增加了 23.3%±8.5%(P<0.001)。复张组 94.4%的患者的影像学肺不张完全改善,且无不良事件,而对照组 87.5%的患者存在一些肺不张(P<0.001)。
带肺复张手法的无创通气安全有效,可改善冠状动脉旁路移植患者的氧合,并减少肺不张。