Kimura Ryoko, Sugita Kazunari, Goto Hiroyuki, Yamamoto Osamu
Division of Dermatology, Department of Medicine of Sensory and Motor Organs, School of Medicine, Tottori University Faculty of Medicine, Yonago 683-8504, Japan.
Yonago Acta Med. 2018 Jun 18;61(2):140-141. doi: 10.33160/yam.2018.06.007. eCollection 2018 Jun.
We report a case of squamous cell carcinoma manifested as a cutaneous horn. A 92-year-old man was referred to our department for evaluation of a 3-month history of a keratotic cutaneous horn on the left side of his neck. The height of the cutaneous horn was larger than the diameter of erythema at the base. Histopathological examination showed a hyperkeratotic horn developing over a mass of large atypical keratinocytes with large hyperchromatic and pleomorphic nuclei. Based on these findings, a diagnosis of squamous cell carcinoma was made. A recent study showed that cutaneous horns in association with invasive squamous cell carcinoma had a tendency to have less height than the diameter of the base. In our case, however, the height of the cutaneous horn was larger than the diameter of the base, indicating that invasive squamous cell carcinoma sometimes shows a cutaneous horn that is higher than the diameter of the base. Thus, clinical finding of erythema at the base of the cutaneous horn would be a reliable feature for early detection of squamous cell carcinoma.
我们报告一例表现为皮角的鳞状细胞癌病例。一名92岁男性因左侧颈部出现角化性皮角3个月前来我院就诊。皮角的高度大于其底部红斑的直径。组织病理学检查显示，在一大团具有大的深染和多形性核的非典型角质形成细胞上形成了角化过度的角。基于这些发现，诊断为鳞状细胞癌。最近一项研究表明，与浸润性鳞状细胞癌相关的皮角往往高度小于底部直径。然而，在我们的病例中，皮角的高度大于底部直径，这表明浸润性鳞状细胞癌有时会表现出高于底部直径的皮角。因此，皮角底部出现红斑这一临床发现将是早期检测鳞状细胞癌的可靠特征。
