Ozsin K K, Sanri U S, Toktas F, Yavuz S
Bratisl Lek Listy. 2018;119(6):335-340. doi: 10.4149/BLL_2018_063.
The aim of this study was to evaluate the relationship between red blood cell distribution width (RDW) and mean platelet volume (MPV) with development of postoperative atrial fibrillation (PoAF) after off-pump coronary artery bypass grafting (CABG).
The RDW and MPV have been associated with some cardiovascular disorders.
A total of 93 patients who underwent off-pump CABG were included in this study. The patients were divided into two groups as developing and nondeveloping PoAF groups in the postoperative period. We measured whether RDW and MPV levels are a predictive value for development PoAF.
There were 24 patients with PoAF enrolled (mean age: 66 ± 7.8 years) and 69 patients without PoAF (mean age: 56.26 ± 11.53 years). The PoAF was significantly correlated with age (p = 0.004), hematocrit (p: 0.010), RDW (p = 0.007) and creatinine (p = 0.006). Only advanced age (p = 0.012) was identified as an independent predictor of PoAF. For predicting PoAF, there was 79.2 % sensitivity and 65.2 % specificity for RDW (p = 0.001) and 62.5 % sensitivity and 55.1 % specificity for MPV (p = 0.062).
We found that RDW levels and MPV were not an independent predictor of the development of PoAF. However, elevated RDW levels and MPV may be one of the predictive values for PoAF development (Tab. 3, Fig. 2, Ref. 27).
本研究旨在评估非体外循环冠状动脉旁路移植术（CABG）后红细胞分布宽度（RDW）和平均血小板体积（MPV）与术后房颤（PoAF）发生之间的关系。
RDW和MPV与一些心血管疾病有关。
本研究共纳入93例行非体外循环CABG的患者。患者在术后分为发生PoAF组和未发生PoAF组。我们测量了RDW和MPV水平对PoAF发生是否具有预测价值。
有24例发生PoAF的患者（平均年龄：66±7.8岁）和69例未发生PoAF的患者（平均年龄：56.26±11.53岁）。PoAF与年龄（p = 0.004）、血细胞比容（p：0.010）、RDW（p = 0.007）和肌酐（p = 0.006）显著相关。仅高龄（p = 0.012）被确定为PoAF的独立预测因素。对于预测PoAF，RDW的敏感性为79.2%，特异性为65.2%（p = 0.001），MPV的敏感性为62.5%，特异性为55.1%（p = 0.062）。
我们发现RDW水平和MPV不是PoAF发生的独立预测因素。然而，升高的RDW水平和MPV可能是PoAF发生的预测指标之一（表3，图2，参考文献27）。
