Land P W, Simons D J
Brain Res. 1985 Aug 19;341(1):189-94. doi: 10.1016/0006-8993(85)91488-x.
Cytochrome oxidase (CO) histochemistry was used to examine the effect of sensory deprivation on metabolic activity in the somatosensory cortex (SmI) of adult rats. Chronic trimming of one or several rows of mystacial vibrissae resulted in a decrease in CO reactivity in the corresponding barrels in layer IV. Reduced CO staining also was observed in cortical laminae superficial and deep to the affected layer IV barrels, suggesting that patterned deflections of the whiskers are important for maintaining the metabolic activity of neurons at least 3 and perhaps 4 synapses removed from the periphery.
细胞色素氧化酶（CO）组织化学法被用于检测感觉剥夺对成年大鼠体感皮层（SmI）代谢活性的影响。对一排或几排触须进行长期修剪，导致IV层相应桶状区的CO反应性降低。在受影响的IV层桶状区浅层和深层的皮质板层中也观察到CO染色减少，这表明触须的模式化偏转对于维持至少与外周相隔3个甚至可能4个突触的神经元的代谢活性很重要。
