4-氨基吡啶、γ-氨基丁酸和荷包牡丹碱对猫脊髓背角神经元皮肤感受野的影响。
Effects of 4-aminopyridine, GABA and bicuculline on cutaneous receptive fields of cat dorsal horn neurons.
作者信息
Saadé N, Jabbur S J, Wall P D
出版信息
Brain Res. 1985 Oct 7;344(2):356-9. doi: 10.1016/0006-8993(85)90814-5.
PMID:2994840
Abstract
4-Aminopyridine (4-AP), bicuculline and GABA were applied locally to dorsal horn cells in the lumbar spinal cord in Nembutal-anaesthetized cats and in spinal cats. 4-AP expanded the cutaneous receptive field of 29 of 33 cells tested. Bicuculline and GABA had little or no effect on receptive field size.
摘要
在戊巴比妥麻醉的猫和脊髓猫中，将4-氨基吡啶（4-AP）、荷包牡丹碱和γ-氨基丁酸（GABA）局部应用于腰段脊髓的背角细胞。4-AP使所测试的33个细胞中的29个细胞的皮肤感受野扩大。荷包牡丹碱和GABA对感受野大小几乎没有影响或没有影响。
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