Ezad Saad, Davies Allan J, Cheema Hooria, Williams Trent, Leitch James
John Hunter Hospital, Hunter New England Health, Newcastle, NSW, Australia.
Cardiol Res Pract. 2018 May 21;2018:2951860. doi: 10.1155/2018/2951860. eCollection 2018.
Australian guidelines advocate primary percutaneous coronary intervention (PPCI) as the reperfusion strategy of choice for ST elevation myocardial infarction (STEMI) in patients in whom it can be performed within 90 minutes of first medical contact; otherwise, fibrinolytic therapy is preferred. In a large health district, the reperfusion strategy is often chosen in the prehospital setting. We sought to identify a distance from a PCI centre, which made it unlikely first medical contact to balloon time (FMCTB) of less than 90 minutes could be achieved in the Hunter New England health district and to identify causes of delay in patients who were triaged to a PPCI strategy.
We studied 116 patients presenting via the ambulance service with STEMI from January 2016 to December 2016. In patients who were taken directly to the cardiac catheterisation lab, a maximum distance of 50 km from hospital resulted in 75% of patients receiving PCI within 90 minutes and approximately 95% of patients receiving PCI within 120 minutes. Patients who bypassed the emergency department (ED) were significantly more likely to have FMCTB of less than 90 minutes ( < 0.001) despite having a longer travel distance (28.5 km versus 17.4 km, < 0.001). Patients transiting via the ED were significantly more likely to present out of hours (60 versus 24.2% < 0.001).
Patients who do not bypass the ED have a longer FMCTB across all spectrum of distances from the PCI centre; therefore, bypassing the ED is key to achieving target FMCTB times. Using a cutoff distance of 50 km may reduce human error in estimating travel time to our PCI centre and thereby identifying patients who should receive prehospital thrombolysis.
澳大利亚指南提倡,对于能在首次医疗接触后90分钟内进行治疗的ST段抬高型心肌梗死(STEMI)患者,首选直接经皮冠状动脉介入治疗(PPCI)作为再灌注策略;否则,首选溶栓治疗。在一个大型健康区,再灌注策略通常在院前环境中选定。我们试图确定一个距PCI中心的距离,在亨特新英格兰健康区,该距离会使首次医疗接触至球囊扩张时间(FMCTB)不太可能少于90分钟,并确定被分诊至PPCI策略的患者出现延迟的原因。
我们研究了2016年1月至2016年12月通过救护车服务就诊的116例STEMI患者。在直接被送往心导管实验室的患者中,距医院最大50公里的距离使得75%的患者在90分钟内接受了PCI,约95%的患者在120分钟内接受了PCI。绕过急诊科(ED)的患者尽管行程距离更长(28.5公里对17.4公里,<0.001),但FMCTB少于90分钟的可能性显著更高(<0.001)。经ED转运的患者在非工作时间就诊的可能性显著更高(60%对24.2%,<0.00)。
未绕过ED的患者在距PCI中心的所有距离范围内都有更长的FMCTB;因此,绕过ED是实现目标FMCTB时间的关键。使用50公里的截止距离可能会减少估计前往我们PCI中心行程时间时的人为误差,从而识别出应接受院前溶栓治疗的患者。