Key Laboratory of the Ministry of Education for Advanced Catalysis Materials, Department of Chemistry, Zhejiang Normal University, 688 Yingbin Road, Jinhua 321004, P. R. China.
Chem Commun (Camb). 2018 Jul 12;54(57):7924-7927. doi: 10.1039/c8cc03105c.
A visible-light induced three-component reaction of difluoroalkyl halides, unactivated alkenes, and alkynyl sulfones is described, providing a direct and general approach to the construction of synthetically valuable β-difluoroalkylated alkynes under room temperature conditions. This represents the first intermolecular alkynyl-difluoroalkylation of unactivated alkenes.
本文描述了一种可见光诱导的二氟烷基卤化物、非活化烯烃和炔基砜的三组分反应，为在室温条件下构建具有合成价值的β-二氟烷基化炔烃提供了一种直接而通用的方法。这代表了首例非活化烯烃的分子间炔基-二氟烷基化反应。
