Med Princ Pract. 2018;27(5):493-495. doi: 10.1159/000491586. Epub 2018 Jun 28.
Acute spontaneous bullous urticaria is an extremely rare entity, and there are few reports with blister formation in acute urticaria patients.
We present a 2-year-old girl who was admitted for bullous spontaneous acute urticaria; the underlying reason for this was not detected. Nikolsky's sign and Darier's sign were negative. Lesions were not compatible with erythema multiforme. However, biopsy was not allowed to be performed. Because of this, the underlying pathogenesis could not be clarified. The patient recovered by a short course of antihistamine and systemic steroid treatment, and the lesions did not recur during a 2-year follow-up.
Short-term systemic steroid in addition to oral antihistamines resulted in prompt recovery in a patient with acute urticaria complicated by bullae.
急性自发性大疱性荨麻疹极为罕见,且急性荨麻疹患者出现水疱的病例报道较少。
我们报告了一例 2 岁女孩,因急性自发性大疱性荨麻疹入院;未发现其潜在病因。尼氏征和 Darier 征均为阴性。皮损与多形红斑不符。但未进行活检。因此,无法明确潜在发病机制。患者经短程抗组胺和全身类固醇治疗后痊愈,2 年随访期间皮损未再复发。
急性荨麻疹并发大疱的患者在口服抗组胺药的基础上加用短期全身类固醇治疗可迅速康复。