Chen Qiang, Lin Ze-Wei, Hong Zhi-Nuan, Cao Hua, Zhang Gui-Can, Chen Liang-Wan, Yu Ling-Li, Zhang Qi-Liang
Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, China.
Thorac Cardiovasc Surg. 2019 Jan;67(1):8-13. doi: 10.1055/s-0038-1660809. Epub 2018 Jun 28.
Transthoracic device closure (TTDC) and surgical repair with right infra-axillary thoracotomy (SRRIAT) or with right submammary thoracotomy (SRSMT) are all the primary alternative treatments for restrictive perimembranous ventricular septal defect (pmVSD). However, few studies have compared them in terms of effectiveness and complications.
Patients with restrictive pmVSD undergoing TTDC, or SRRIAT, or SRSMT from March 2016 to February 2017 were retrospectively reviewed in our cardiac center. There were no differences in age (1.3 ± 1.2 vs 1.1 ± 1.1 vs 1.2 ± 1.1 years), gender (35/37 vs 30/33 vs 29/29), body weight (8.3 ± 2.6 vs 8.2 ± 2.4 vs 8.1 ± 2.5 kg), and size of VSD (4.2 ± 1.1 vs 5.2 ± 1.3 vs 5.1 ± 1.2 mm) distribution between the three groups.
The procedure success rates were similar in the three groups. The TTDC group had the shortest operative time, postoperative mechanical ventilation time, duration of intensive care, postoperative length of hospital stay, medical cost, and length of the incision. There were no significant differences in terms of operative time, aortic cross-clamping time, duration of cardiopulmonary bypass (CPB), blood transfusion volume, mechanical ventilation time, duration of intensive care, duration of hospital stays, pleural fluid drainage, or cost between the SRSMT and SRRIAT groups. No significant differences were noted in terms of major adverse events.
TTDC, SRRIAT, and SRSMT all showed excellent outcomes and cosmetic appearances for selected VSD patients. TTDC had advantages over SRRIAT and SRSMT in terms of short operation duration and smaller incision size and shorter durations of intensive care and hospital stays.
经胸封堵术(TTDC)以及采用右腋下胸廓切开术(SRRIAT)或右乳房下胸廓切开术(SRSMT)进行外科修复,都是限制性膜周部室间隔缺损(pmVSD)的主要替代治疗方法。然而,很少有研究在有效性和并发症方面对它们进行比较。
对2016年3月至2017年2月在我们心脏中心接受TTDC、SRRIAT或SRSMT治疗的限制性pmVSD患者进行回顾性分析。三组患者在年龄(1.3±1.2岁 vs 1.1±1.1岁 vs 1.2±1.1岁)、性别(35/37 vs 30/33 vs 29/29)、体重(8.3±2.6 kg vs 8.2±2.4 kg vs 8.1±2.5 kg)以及室间隔缺损大小(4.2±1.1 mm vs 5.2±1.3 mm vs 5.1±1.2 mm)分布上无差异。
三组手术成功率相似。TTDC组手术时间、术后机械通气时间、重症监护时间、术后住院时间、医疗费用和切口长度最短。SRSMT组和SRRIAT组在手术时间、主动脉阻断时间、体外循环(CPB)时间、输血量、机械通气时间、重症监护时间、住院时间、胸腔引流量或费用方面无显著差异。在主要不良事件方面未观察到显著差异。
对于选定的室间隔缺损患者,TTDC、SRRIAT和SRSMT均显示出良好的治疗效果和美观效果。TTDC在手术时间短、切口小、重症监护和住院时间短方面优于SRRIAT和SRSMT。