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基于磨损颗粒分析的人工关节失效磨损机制

Wear Mechanism of Artificial Joint Failure Using Wear Debris Analysis.

作者信息

Zhang Daoming, Liu Hongtao, Wang Jianmei, Sheng Chenxing, Li Zhixiong

出版信息

J Nanosci Nanotechnol. 2018 Oct 1;18(10):6805-6814. doi: 10.1166/jnn.2018.15513.

DOI:10.1166/jnn.2018.15513
PMID:29954497
Abstract

Aseptic loosening is one of the main failure modes in artificial joints. Significant information about the aseptic loosening is carried by the wear debris of the joints. In this paper, the wear debris acquired from the ultrahigh molecular weight polyethylene (UHMWPE) artificial joints is prepared and a systematic research is carried out to investigate the wear mechanism of aseptic loosening using the wear debris analysis. The hip joint simulator was used to conduct the wear tests of the CoCrMo-UHMWPE artificial joint friction pairs. The scanning electron microscope (SEM) was employed to analyze the wear debris profiles. The analysis results demonstrated that the UHMWPE joints mainly produced the roundness, tuberous, lacerated, sheet, pole-liked and strip wear debris, and the wear mechanism of the joint aseptic loosening had a close relationship with the morphology of the debris types. The adhesive wear, fatigue wear and laceration under alternating stress were the main causes of the joint failure. Based on the wear debris analysis results, a new diagnosis method using the radar map fractal representation was proposed to diagnose the failure of the artificial joints.

摘要

无菌性松动是人工关节的主要失效模式之一。有关无菌性松动的重要信息由关节的磨损颗粒携带。本文制备了从超高分子量聚乙烯(UHMWPE)人工关节获取的磨损颗粒,并利用磨损颗粒分析对无菌性松动的磨损机制进行了系统研究。使用髋关节模拟器对CoCrMo-UHMWPE人工关节摩擦副进行磨损试验。采用扫描电子显微镜(SEM)分析磨损颗粒轮廓。分析结果表明,UHMWPE关节主要产生圆形、结节状、撕裂状、片状、杆状和条状磨损颗粒,关节无菌性松动的磨损机制与颗粒类型的形态密切相关。粘着磨损、疲劳磨损和交变应力下的撕裂是关节失效的主要原因。基于磨损颗粒分析结果,提出了一种利用雷达图分形表示法诊断人工关节失效的新方法。

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The effect of intra-articular injection of antibacterial drugs in the clinical treatment of prosthetic joint infection in patients undergoing artificial hip replacement.关节腔内注射抗菌药物在人工髋关节置换患者人工关节感染临床治疗中的作用。
Am J Transl Res. 2021 Apr 15;13(4):3508-3514. eCollection 2021.