Okubo Saki, Fujioka Kazumichi, Yamane Megumi, Ashina Mariko, Fukushima Sachiyo, Ikuta Toshihiko, Ohyama Shohei, Yamana Keiji, Kobayashi Akiko, Iijima Kazumoto, Morioka Ichiro
Department of Pediatrics, Kobe University Graduate School of Medicine, Kobe, Japan.
Department of Pediatrics, National Hospital Organization Kobe Medical Center, Kobe, Japan.
Kobe J Med Sci. 2018 Apr 19;63(4):E105-E108.
We reported a term newborn case of early onset sepsis caused by nontypeable Haemophilus Influenzae (NTHi) with massive bacterial invasion in the placenta. Based on the consistent results of maternal placental pathology and neonatal bacterial culture, we diagnosed this as vertical transmission of NTHi via vaginal delivery. In general, NTHi infections occur in preterm infants, and our term infant case is very unusual. In conclusion, clinicians should consider NTHi as a cause of neonatal sepsis, even in term infants.
我们报告了一例足月儿早发型败血症病例,由不可分型流感嗜血杆菌(NTHi)引起,胎盘存在大量细菌侵袭。基于母亲胎盘病理学检查和新生儿细菌培养的一致结果,我们将此诊断为NTHi经阴道分娩的垂直传播。一般来说,NTHi感染发生在早产儿中,而我们的足月儿病例非常罕见。总之,临床医生应将NTHi视为新生儿败血症的病因,即使是在足月儿中。