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预测老年肺癌患者肺叶切除术后并发症的风险评分。

A risk score to predict postoperative complications after lobectomy in elderly lung cancer patients.

作者信息

Kawaguchi Yo, Hanaoka Jun, Ohshio Yasuhiko, Igarashi Tomoyuki, Kataoka Yoko, Okamoto Keigo, Kaku Ryosuke, Hayashi Kazuki

机构信息

Division of General Thoracic Surgery, Department of Surgery, Shiga University of Medical Science, Tsukinowacho, Seta, Otsu, Shiga, 502-2192, Japan.

Division of General Thoracic Surgery, Kusatsu General Hospital, Kusatsu, Shiga, Japan.

出版信息

Gen Thorac Cardiovasc Surg. 2018 Sep;66(9):537-542. doi: 10.1007/s11748-018-0960-8. Epub 2018 Jun 28.

Abstract

OBJECTIVE

In elderly patients with lung cancer, the presumed fear of postoperative complications has resulted in the delivery of limited resection. Surgical decision-making for such patients would become easier if clinicians could predict who is at high risk of postoperative complications. The purpose of this study is to propose a scoring system to predict the risk of postoperative complications for elderly patients with lung cancer.

METHODS

We reviewed patients aged 75 years or older who underwent lobectomy for lung cancer at a single hospital (n = 199). A multivariable logistic regression model was utilized to determine risk factors for postoperative complications.

RESULTS

Six risk factors for postoperative complications were identified, and we derived a risk score by assigning weights to these factors based on their odds ratios, as follows: Risk score = 7 × (performance status of 2) + 6 × (coronary artery disease) + 3 × (a history of cerebrovascular accident) + 2 × (restrictive ventilatory impairment) + 1 × (male sex) + 1 × (interstitial pneumonia). The postoperative complication rates in patients with risk scores of 0, 1-2, 3-5, 6-8, and 9-14 were 19, 29, 56, 68, and 90%, respectively.

CONCLUSIONS

The proposed risk score was able to predict the incidence of postoperative complications. The risk score can be used to identify high-risk patients and to select proper treatment strategies.

摘要

目的

在老年肺癌患者中,对术后并发症的担忧导致了有限切除术的实施。如果临床医生能够预测哪些患者术后并发症风险高,那么这类患者的手术决策将变得更加容易。本研究的目的是提出一种评分系统,以预测老年肺癌患者术后并发症的风险。

方法

我们回顾了在一家医院接受肺癌肺叶切除术的75岁及以上患者(n = 199)。采用多变量逻辑回归模型确定术后并发症的危险因素。

结果

确定了术后并发症的六个危险因素,并根据这些因素的优势比为其赋予权重,得出风险评分如下:风险评分 = 7×(体能状态为2)+ 6×(冠状动脉疾病)+ 3×(脑血管意外病史)+ 2×(限制性通气功能障碍)+ 1×(男性)+ 1×(间质性肺炎)。风险评分为0、1 - 2、3 - 5、6 - 8和9 - 14的患者术后并发症发生率分别为19%、29%、56%、68%和90%。

结论

所提出的风险评分能够预测术后并发症的发生率。该风险评分可用于识别高危患者并选择合适的治疗策略。

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