Liang Ching-Chung, Hsieh Wu-Chiao, Huang Lulu
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan.
College of Medicine, Chang Gung University, Taoyuan, Taiwan.
J Obstet Gynaecol Res. 2018 Aug;44(8):1466-1471. doi: 10.1111/jog.13683. Epub 2018 Jun 28.
To demonstrate the clinical and urodynamic outcomes of transobturator sling (TOT) with or without concomitant prolapse surgery for the treatment of urodynamic stress incontinence (USI).
We recruited 143 consecutive patients diagnosed with USI, who received outside-in TOT in a university hospital. Preoperative and postoperative examinations were implemented using structured urogynecological questionnaires, pelvic organ prolapse quantification examination and urodynamic testing. Patient demographics, surgical and urodynamic results were compared between TOT with and without concomitant prolapse surgery.
The mean follow-up was 30.1 months (range 12-57). Postoperative stress urinary incontinence (SUI) occurred in 10 (7%) patients at 3 months and 10 (7%) patients at 12 months postoperatively. There was no significant difference in prevalence of postoperative SUI between groups of TOT only and TOT combined with pelvic surgery. Preoperative urodynamic results demonstrated that TOT only (n = 96) had a higher maximal flow rate and a lower residual urine amount when compared to TOT combined with pelvic surgery (n = 47). A significant decrease in maximal urethral closure pressure (MUCP) was found in 119 patients who received postoperative urodynamic examination. In comparison with preoperative urodynamic data, postoperative urodynamic results showed a significant decrease in MUCP in the TOT combined with prolapse surgery group, but no significant urodynamic changes in the group of TOT only.
Both TOT and TOT combined with prolapse surgery can be effective in correcting SUI in patients with USI 12 months postoperatively, with significant changes in MUCP.
探讨经闭孔尿道中段无张力悬吊术(TOT)单独或联合盆底脱垂手术治疗女性压力性尿失禁(USI)的临床及尿动力学疗效。
连续纳入143例诊断为USI并行TOT手术的患者,采用前瞻性、自身对照研究方法,在大学附属医院行TOT手术,术前及术后分别采用标准化问卷、盆腔器官脱垂定量分期系统(POP-Q)及尿动力学检查评估患者情况。比较单纯TOT手术组和联合盆底脱垂手术组患者的人口学资料、手术及尿动力学结果。
平均随访时间30.1个月(12-57个月)。术后3个月和12个月分别有10例(7%)患者出现压力性尿失禁(SUI)。单纯TOT组和联合盆底手术组术后SUI发生率差异无统计学意义。术前尿动力学结果显示,单纯TOT组(n = 96)最大尿流率高于联合盆底手术组(n = 47),残余尿量低于联合盆底手术组。术后119例患者行尿动力学检查,最大尿道闭合压(MUCP)均显著下降。与术前比较,联合盆底手术组术后MUCP下降显著,单纯TOT组无显著变化。
TOT及联合盆底脱垂手术治疗USI术后12个月均能有效改善SUI,MUCP均有显著变化。