1 German Aortic Center Hamburg, Department of Vascular Medicine, University Heart Center, Hamburg, Germany.
J Endovasc Ther. 2018 Aug;25(4):466-473. doi: 10.1177/1526602818783506. Epub 2018 Jun 29.
To analyze the renal function and outcome after delayed (>6 hours) endovascular revascularization of acute renal artery occlusion (RAO) in patients with fenestrated-branched endovascular aneurysm repairs (EVARs) or open visceral debranching.
A single-center retrospective analysis was conducted involving 7 patients (mean age 61 years, range 49-72; 5 women) with 9 RAOs treated with endovascular revascularization between December 2014 and March 2017. Three patients had a solitary kidney with chronic renal insufficiency; 1 patient had bilateral occlusions as the acute event. Initial aortic surgery included 5 branched and 1 fenestrated EVAR as well as 1 open visceral debranching operation. Revascularization of the RAO was performed using aspiration thrombectomy, local lysis therapy, and stent-graft relining. The median time between initial aortic surgery and RAO was 10 months (range 0.5-17).
Median renal ischemic time to revascularization was 24 hours (range 7-168). Technical success was 100%, with 1 procedure-related access complication. Temporary dialysis dependency occurred in 4 patients. Mean in-hospital stay was 17 days (range 7-32) with 1 postoperative death at day 10 due to cardiac arrest of unknown cause. Mean follow-up was 10.3 months (range 1.5-27) in 5 of 6 discharged patients. During follow-up, 1 reintervention for recurrent occlusion was performed. At follow-up imaging, all renal arteries were patent. No permanent dialysis dependency occurred.
Renal function can be salvaged by delayed revascularization for RAO with prolonged renal ischemia. The endovascular approach with aspiration thrombectomy, local lysis, and stent-graft relining is a feasible technique for revascularization after RAO in patients with fenestrated-branched EVAR or open visceral debranching.
分析腔内血管重建治疗开窗/分支型腹主动脉瘤腔内修复术(EVAR)或开放内脏动脉去分支术后急性肾动脉闭塞(RAO)的肾功能及预后。
回顾性分析 2014 年 12 月至 2017 年 3 月间 7 例(平均年龄 61 岁,范围 49-72 岁;5 例女性)接受腔内血管重建治疗的 9 例 RAO 患者的临床资料。3 例患者为孤立肾伴慢性肾功能不全;1 例患者为双侧急性闭塞。初次主动脉手术包括 5 例分支型和 1 例开窗型 EVAR 及 1 例开放内脏动脉去分支术。RAO 的腔内血管重建采用抽吸血栓切除术、局部溶栓治疗和支架移植物再衬。初次主动脉手术后至 RAO 的中位时间为 10 个月(范围 0.5-17 个月)。
RAO 血管再通的中位缺血时间为 24 小时(范围 7-168 小时)。技术成功率为 100%,1 例手术相关血管入路并发症。4 例患者需临时透析。中位住院时间为 17 天(范围 7-32 天),1 例患者术后第 10 天因不明原因心跳骤停死亡。6 例出院患者中有 5 例获得中位 10.3 个月(范围 1.5-27 个月)的随访。随访期间,1 例患者因再发闭塞行再次介入治疗。随访影像学检查显示所有肾动脉均通畅。无永久性透析依赖。
即使肾动脉缺血时间较长,RAO 延迟血管再通也可挽救肾功能。抽吸血栓切除术、局部溶栓和支架移植物再衬的腔内治疗方法是开窗/分支型 EVAR 或开放内脏动脉去分支术后 RAO 血管再通的一种可行技术。