Staartjes Victor E, Schröder Marc L
1Department of Neurosurgery, Bergman Clinics, Amsterdam, The Netherlands; and.
2Faculty of Medicine, University of Zurich, Switzerland.
J Neurosurg Spine. 2018 Oct;29(4):380-387. doi: 10.3171/2018.2.SPINE171416. Epub 2018 Jun 29.
Recently, objective functional tests have generated interest since they can supplement an objective dimension to clinical assessment. The five-repetition sit-to-stand (5R-STS) test is a quick and objective tool that tests movements frequently used in everyday life. The aim of this prospective study was to evaluate the validity and reliability of the 5R-STS test in patients with degenerative pathologies of the lumbar spine.
Patients and healthy volunteers completed the standardized 5R-STS, Roland-Morris Disability Questionnaire (RMDQ), Oswestry Disability Index (ODI), visual analog scale (VAS) for back and leg pain, and EQ-5D for health-related quality of life (HRQOL). To assess convergent validity, the 5R-STS test times were correlated with these questionnaires.
Overall, 157 patients and 80 volunteers were enrolled. Direct correlation with RMDQ (r = 0.49), ODI (r = 0.44), and VAS for back pain (r = 0.31) and indirect correlation with the EQ-5D index (r = -0.41) were observed (p < 0.001). The 5R-STS test showed no correlation with VAS for leg pain and EQ-5D VAS (p > 0.05). In 119 individuals, the 5R-STS test demonstrated excellent test-retest reliability with an intraclass correlation coefficient of 0.98. The upper limit of normal, distinguishing patients with and without objective functional impairment, was identified as 10.35 seconds. A severity stratification classified patients with test times of 10.5-15.2, 15.3-22.0, or greater than 22.0 seconds as having mild, moderate, or severe functional impairment, respectively.
The 5R-STS test is a simple and effective tool to describe objective functional impairment. A patient able to perform the test in 10.4 seconds can be considered to have no relevant objective functional impairment. Clinical trial registration no.: NCT03303300 (clinicaltrials.gov).
近年来,客观功能测试引发了人们的兴趣,因为它们可以为临床评估补充客观维度。五次重复坐立试验(5R-STS)是一种快速且客观的工具,用于测试日常生活中常用的动作。这项前瞻性研究的目的是评估5R-STS测试在腰椎退行性病变患者中的有效性和可靠性。
患者和健康志愿者完成标准化的5R-STS、罗兰-莫里斯残疾问卷(RMDQ)、奥斯维斯特里残疾指数(ODI)、背部和腿部疼痛视觉模拟量表(VAS)以及与健康相关生活质量(HRQOL)的EQ-5D。为评估收敛效度,将5R-STS测试时间与这些问卷进行相关性分析。
总共招募了157名患者和80名志愿者。观察到与RMDQ(r = 0.49)、ODI(r = 0.44)以及背部疼痛VAS(r = 0.31)呈直接相关性,与EQ-5D指数呈间接相关性(r = -0.41)(p < 0.001)。5R-STS测试与腿部疼痛VAS和EQ-5D VAS无相关性(p > 0.05)。在119名个体中,5R-STS测试显示出极好的重测可靠性,组内相关系数为0.98。正常上限,即区分有无客观功能障碍患者的界限,确定为10.35秒。严重程度分层将测试时间为10.5 - 15.2秒、15.3 - 22.0秒或大于22.0秒的患者分别归类为轻度、中度或重度功能障碍。
5R-STS测试是描述客观功能障碍的一种简单有效的工具。能够在10.4秒内完成测试的患者可被认为没有相关的客观功能障碍。临床试验注册号:NCT03303300(clinicaltrials.gov)。