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[硬皮病样迟发性皮肤卟啉病。超微结构研究]

[Sclerodermiform porphyria cutanea tarda. Ultrastructural study].

作者信息

Ocaña J, Pérez de Vargas I, Wilhelmi M L, Crespo V, Pastor R, Fajardo F S, Delgado M L

出版信息

Med Cutan Ibero Lat Am. 1985;13(2):157-66.

PMID:2995737
Abstract

Approximately 30% of patients affected of PCT present scleroderma-like lesion of the skin. Two cases of PCT, presenting scleroderma-like lesions are reported. The patients were diabetic but not alcoholic and tolerate relatively well sunshine. Porphyrin elimination diminished with urine alkalinization and phlebotomies, and the scleroderma-like lesions improved with N-acetyl-hydroxy-proline administration.

摘要

约30%的迟发性皮肤卟啉病患者出现硬皮病样皮肤病变。本文报告了2例出现硬皮病样病变的迟发性皮肤卟啉病病例。患者患有糖尿病但非酒精性,对阳光耐受性相对较好。随着尿液碱化和放血治疗,卟啉排泄减少,给予N-乙酰羟脯氨酸后硬皮病样病变有所改善。

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