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[局部播散性及复发性直肠癌放疗及综合治疗中的热疗与高血糖症]

[Hyperthermia and hyperglycemia in the radiation and combined treatment of locally disseminated and recurrent rectal cancer].

作者信息

Knysh V I, Goldobenko G V, Barkanov A I, Ozhiganov E L, Timofeev Iu M

出版信息

Med Radiol (Mosk). 1985 Sep;30(9):32-7.

PMID:2995756
Abstract

The results of the use of short-term induced hyperglycemia and local UHF-hyperthermia in radiation therapy of 27 rectal cancer patients aged 17 to 65 were analysed. A primary inoperable locally disseminated tumor process was noted in 8 patients, recurring cancer in 19. A noticeable tumor regression (over 50%) was observed in 7 out of 8 patients making a radical operation possible. With computerized tomography tumor regression was recorded by over 50% in 9 out of 19 nonoperated patients. The data obtained illustrate some potentialities of raising the efficacy of radiotherapy using radiomodifiers.

摘要

分析了17至65岁的27例直肠癌患者在放射治疗中使用短期诱导高血糖和局部超高频热疗的结果。8例患者存在原发性不可手术的局部播散性肿瘤,19例为复发性癌症。8例患者中有7例出现明显的肿瘤消退(超过50%),使得根治性手术成为可能。在19例未手术的患者中,通过计算机断层扫描记录到9例患者的肿瘤消退超过50%。所获得的数据说明了使用放射增敏剂提高放射治疗疗效的一些潜力。

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